 2016 East Tennessee State Buccaneers football team

The 2016 East Tennessee State Buccaneers football team represented East Tennessee State University (ETSU) in the 2016 NCAA Division I FCS football season and were in the first year of their second stint as football members of the Southern Conference (SoCon).ETSU had originally joined the SoCon in 1978, with football joining in 1979, but dropped the sport after the 2003 season and left the conference entirely in 2005.