 Tisquesusa was the ruler of the southern Muisca Confederation at the time of the Spanish conquest of the Muisca, when the troops led by Gonzalo Jiménez de Quesada and his brother entered the central Colombian highlands.His "zaque" counterpart in the northern area of the Muisca was Quemuenchatocha.Tisquesusa was "cacique" of Chía and following the Muisca heritage rules, he as nephew of the previous ruler Nemequene succeeded his uncle in 1514.