 This pattern is found in sarcomas and carcinomas, and in tumors of human and rodent origin Thus, SDH is significant in the development of hyperglycemia and tumors.In addition, homocystinuria is a hereditary disease caused by the deficiency of L-serine dehydratase.Its symptoms include mental retardation, death, atherosclerosis, and coronary thrombosis as well as dislocation of the eye lens.