 Also, solenopsins have been demonstrated to inhibit cell division and viability of Trypanosoma cruzi, the cause of Chaga's disease, which suggests these alkaloids as potential chemotherapeutic drugs.Solenopsin and analogs share structural and biological properties with the sphingolipid ceramide, a major endogenous regulator of cell signaling, inducing mitophagy and anti-proliferative effects in different tumor cell lines.Synthetic analogs of solenopsin are being studied for the potential treatment of psoriasis.