 The Sasanian Empire conquered Assyria and Mesopotamia from the Parthians during the 220s, and by 260 had abolished these city-states, with the 3000-year-old city of Assur being sacked in 256.Some regions appear to have remained partly autonomous as late as the latter part of the fourth century, with an Assyrian king named Sinharib reputedly ruling a part of Assyria in the 370s.Between 633-8, the region was invaded by the Arabs during the Muslim conquest of Persia; together with Meshan, it became the province of al-ʿIrāq.