 Immunodeficiency is also seen with this disease, but it is a sequela to the condition and not a predisposing factor.The classical laboratory finding is polyclonal hypergammaglobulinemia, and other immunoglobulin derangements are also seen, including hemolytic anemia with cold agglutinins, circulating immune complexes, anti-smooth muscle antibodies, and positive rheumatoid factor.The normal architecture of a lymph node is partially effaced by a polymorphous infiltrate and residual follicles are commonly seen.