 He also founded the city of Guayaquil in what is now Ecuador.Orellana died during a second expedition on the Amazon.Born in Trujillo (various birth dates, ranging from 1490 to 1511, are still quoted by biographers), Orellana was a close friend and possibly a relative of Francisco Pizarro, the Trujillo-born conquistador of Peru (his cousin, according to some historians).