 Her final reign from 124 BC to 116 BC was also spent in coregency with Ptolemy VIII and Cleopatra III.Cleopatra II was the daughter of Ptolemy V and likely Cleopatra I.If she was the daughter of Cleopatra I, she was a full sister of Ptolemy VI Philometor and Ptolemy VIII Euergetes II Tryphon; otherwise she was their half-sister.