 According to the U.S. Census Bureau, the county has a total area of , of which is land and (0.2%) is water.The Calhoun County Airport is a county-owned public-use airport located one nautical mile (1.2 mi, 1.9 km) southwest of the central business district of Pittsboro, Mississippi.As of the census of 2000, there were 15,069 people, 6,019 households, and 4,255 families residing in the county.