 The major highway through Clarendon is U.S. Highway 79, which gives access to Stuttgart to the south, Marianna to the east and Brinkley (via U.S. Highway 49) to the north.Within the city, U.S. Highway 79B serves the central business district.Highway 302 is a north–south highway that begins at Madison Street in Clarendon and runs north to Highway 17 very near U.S. Highway 70.