 Arkansas Highway 119 connects the city with the east-west oriented Arkansas Highway 18 to the south.Ecologically, Leachville is located within the St. Francis Lowlands ecoregion within the larger Mississippi Alluvial Plain.The St. Francis Lowlands are a flat region mostly covered with row crop agriculture today, though also containing sand blows and sunken lands remaining from the 1811–12 New Madrid earthquakes.