 In 2007, more than half a century after the modern synthesis, Massimo Pigliucci called for an extended evolutionary synthesis to incorporate aspects of biology that had not been included or had not existed in the mid-20th century.It revisits the relative importance of different factors, challenges assumptions made in the modern synthesis, and adds new factors such as multilevel selection, transgenerational epigenetic inheritance, niche construction, and evolvability.In 2009, Darwin's 200th anniversary, the "Origin of Species" 150th, and the 200th of Lamarck's "early evolutionary synthesis", "Philosophie Zoologique", the evolutionary biologist Eugene Koonin stated that while "the edifice of the [early 20th century] Modern Synthesis has crumbled, apparently, beyond repair", a new 21st century synthesis could be glimpsed.