 The regency of Castile passed on to Ximenez Cisneros and Adrian of Utrecht who were guardians for the under-age Prince Charles.Las Casas was resolved to see Prince Charles who resided in Flanders, but on his way there he passed Madrid and delivered to the regents a written account of the situation in the Indies and his proposed remedies.This was his ""Memorial de Remedios para Las Indias"" of 1516.