 Urushiol binds to the skin on contact, where it causes severe itching that develops into reddish inflammation or uncoloured bumps, and then blistering.These lesions may be treated with Calamine lotion, Burow's solution compresses, dedicated commercial poison ivy itch creams, or baths to relieve discomfort, though recent studies have shown some traditional medicines to be ineffective.Over-the-counter products to ease itching—or simply oatmeal baths and baking soda—are now recommended by dermatologists for the treatment of poison ivy.