 Formic acid can be used as a fuel cell (it can be used directly in formic acid fuel cells and indirectly in hydrogen fuel cells).It is possible to use formic acid as an intermediary to produce isobutanol from CO2 using microbes

Formic acid is often used as a component of mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) analysis and separation techniques for the separation of hydrophobic macromolecules, such as peptides, proteins and more complex structures including intact viruses.Especially when paired with mass spectrometry detection, formic acid offers several advantages over the more traditionally used phosphoric acid.