 Pueyrredón was the only son of Juan Martín de Pueyrredón, then the Supreme Director of the United Provinces of the Río de la Plata, and María Calixta Tellechea y Caviedes, an aristocrat.He completed his primary education at the upper-class Colegio de la Independencia.In 1835 his family relocated to Europe, where he completed his education.