 Entrepreneurial focused, he was known as the "advertising dentist" and eventually had a chain of six "painless extraction" dentist parlors.His chain of dentist offices provided him the opportunity to speculate in the burgeoning California real estate market, financing much of the rebuilding of the SF Business district after the earthquake, making Doc Strub a very wealthy man.One of the San Francisco buildings he built was 450 Sutter, which still houses medical professionals.