 In the same way, secretion of XCL1 encourages Cytotoxic T cells to also communicate with DC containing SCR1.The pair of XCL1 and XCR1 are known to be involved in cross-presentation, antigen uptake, and induction of innate as well as adaptive cytotoxic immunity.XCL1 is also known to increate T cells in joints that are effected with rheumatoid arthritis.