 In Case 3, they reported the patient to be cured with high divided dose tinidazole therapy.They used a higher dosage of the drug (total dose, 14–56 g) than the recommended standard dosage (total dose, 3 g) and observed a significant adverse reaction (poorly tolerated nausea) only with the very high dose (total dose, 56 g).While confirming the safety of the drug, they showed nitazoxanide is ineffective for the treatment of trichomoniasis.