 Apert's medical research primarily dealt with genetic diseases and congenital abnormalities.In 1906 he published the case report "De l'acrocéphalosyndactylie" (Acrocephalosyndactyly), documenting several individuals who had congenital malformations of the skull in conjunction with joined fingers.The condition came to be known as Apert syndrome, a syndrome consisting of a triad of disorders; namely, craniosynostosis, syndactyly, and maxillary underdevelopment.