 CART is also found in a subset of retinal ganglion cells (RGCs), the primary afferent neurons in the retina.Specifically, it labels ON/OFF Direction Selective Ganglion Cells (ooDSGCs), a subpopulation of RGCs that stratify in both the ON and OFF sublamina of the Inner Plexiform Layer (IPL) of the retina.It is also found in a subset of amacrine cells in the Inner Nuclear Layer.