 The highways heads to the northeast, and reaches the eastern terminus at the New York-Pennsylvania border in Damascus Township, where PA 652 crosses the Narrowsburg–Darbytown Bridge over the Delaware River and into New York, continuing as New York State Route 52 (NY 52) and County Route 24 (CR 24) in Sullivan County.The highway originated as the easternmost stretch of US 106 when the United States Highway System was first put together in 1926.The route, however, was assigned as a state highway in 1920.