 The family were well to-do, and of the ten children, seven survived into adulthood.Isotta's mother, Bianca Borromeo ensured that the children all received fine humanist educations, although she was herself illiterate.Two of her daughters, Isotta and her younger sister Ginevra, became renowned for their classical studies, although Ginevra gave up her humanist writing upon her marriage in 1438.