 Reid was head of the firm Reid, Irving & Co., and later a Director (1820 to 1847) of the Bank of England, except when acting as Deputy Governor (1837 to 1839) or Governor (1839 to 1841).In June 2020 the Bank of England issued a public apology for the involvement of Reid, amongst other employees, in the slave trade following the investigation by the Centre for the Study of the Legacies of British Slave-ownership at UCL.He married Maria Louisa, the daughter of Richard Eaton of Stetchworth Park, Cambridgeshire with whom he had 2 sons and a daughter.