 Her mother married secondly Sir Philip Butler, but it is not known whether she had additional children.On 19 April 1598, when she was about eighteen years old, Lettice married Sir Robert Digby (1574 – 24 May 1618), a landed aristocrat of Coleshill, Warwickshire, whose brother was John Digby, 1st Earl of Bristol.The couple resided in Ireland where Sir Robert held the office of MP for Athy, County Kildare in 1613.