 Pröpper made 11 appearances in the Eredivisie in the 2009–10 season.In his second season at Vitesse he scored his first goal for the club, opening an eventual 2–4 defeat to Ajax.On 8 December 2015, Pröpper scored the winning goal for PSV at home against CSKA Moscow in the UEFA Champions League, ensuring a spot in the last 16 for PSV for the first time in nine years.