 Despite these challenges, researchers have attempted to use measures of information integration and differentiation to assess levels of consciousness in a variety of subjects.For instance, a recent study using a less computationally-intensive proxy for formula_12 was able to reliably discriminate between varying levels of consciousness in wakeful, sleeping (dreaming vs. non-dreaming), anesthetized, and comatose (vegetative vs. minimally-conscious vs. locked-in) individuals.IIT also makes several predictions which fit well with existing experimental evidence, and can be used to explain some counterintuitive findings in consciousness research.