 Set at a small American mission in China in 1947, at a time of civil war, it stars Humphrey Bogart masquerading as a Catholic priest and Gene Tierney in the role of a nurse, with a supporting cast including Lee J. Cobb, Agnes Moorehead, E. G. Marshall, and Carl Benton Reid.While playing Anne Scott, Tierney became ill. Bogart had a personal experience as he was close to a sister who suffered from mental illness, so during the production, he fed Tierney her lines and encouraged her to seek help.In 1947, Catholic priest Father O'Shea (Humphrey Bogart) makes his way to a remote mission in China to replace a priest who was killed there.