 He was relieved of his duties in 1950 for political reasons contingent upon the Cold War, and later was one of the 11 signatories to the Russell-Einstein Manifesto in 1955.The CEA was created by Charles de Gaulle on 18 October 1945.Its mandate is to conduct fundamental and applied research into many areas, including the design of nuclear reactors, the manufacturing of integrated circuits, the use of radionuclides for medical treatments, seismology and tsunami propagation, and the safety of computerized systems.