 Isadore, Sr. had immigrated to the United States from Germany in 1815; he served in the Mexican-American War and became a banker in Galveston, Texas.He attended a private school in Galveston, the New York Grammar School, and the Bellevue High School in Bellevue, Virginia.He graduated from Sheffield Scientific School at Yale in 1887, studied at the University of Virginia from 1887 to 1888, and received his M. D. at Tulane in 1889.