 There is a First Nation village of the Tanakteuk subdivision of the Kwakwaka'wakw peoples at the mouth of the river, Tsawatti.Located on the Indian Reserve of the same name, it is the primary eulachon fishing and preservation site of the Kwakwaka'wakw peoples and as such is open for use by other subdivisions of the Kwakwaka'wakw.The Klinaklini River originates in small, unnamed lakes on the eastern slopes of Hellraving Peak, in the northern Pantheon Range, north of Mount Vishnu and Mount Waddington, and south of Perkins Peak.