 Further names and boundaries have evolved over time due to development or changes in demographics.Woodward Avenue, a major a north–south thoroughfare, serves as a demarcation for neighborhood areas on the east side and west side of the city.Downtown Detroit is the city's central business district and a residential area, bordered by M-10 (Lodge Freeway) to the west, the Interstate 75 (I-75, Fisher Freeway) to the north, I-375 (Chrysler Freeway) to the east, and the Detroit River to the south.