 The purportedly cross-reactive autoantibodies may migrate to the skin in dermatitis herpetiformis.IgA deposits may form if the antibodies cross-react with epidermal transglutanimase (eTG).Some patients have eTG-specific antibodies instead of tTG-specific cross-reactive antibodies and the relationship between dermatitis herpetiformis and celiac disease in these patients is not fully understood.