 The beneficial effects of landiolol have been demonstrated in over sixty clinical trials (pubmed search -August 2018).Landiolol was generally well tolerated, with a relatively low risk of hypotension and bradycardia.Most clinical trials with landiolol have been conducted in peri-operative settings for the treatment or prophylaxis of supraventricular tachycardia or tachyarrhythmia before or after cardiac and non-cardiac surgeries.