 TLR5 has been linked with the asthma phenotype experimentally and in human subjects.An important finding in the study was that monkeys over 200 miles away from the combustion were still found to have significant immune and respiratory changes.The findings were consistent with many other human group studies and suggest that children who underwent the same experience as the monkeys in the study have a high chance of exhibiting similar health problems but, that because normal development of rhesus monkeys is accelerated compared to human children the relative impact of this amount of wildfire smoke exposure might differ.