 Iskaka was incorporated into the Ottoman Empire in 1517 with all of Palestine, and in 1596 it appeared in the tax registers under the name of "Skaka", as being in the "nahiya" ("subdistrict") of Jabal Qubal, part of the Sanjak of Nablus.It had a population of 37 households; who were all Muslims.They paid a fixed tax-rate of 33,3 % on agricultural products, including wheat, barley, summer crops, olive trees, goats and beehives, in addition to occasional revenues, a press for olive oil or grape syrup; a total of 5,042 akçe.