 Other adverse events (≥5% of patients) included diarrhea (13%), headache (13%), abdominal distension (5%), abdominal pain (5%), flatulence (6%), sinusitis (5%), vomiting (5%), and fecal incontinence (1%).There is no current data on use in people with liver or kidney complications.The effects on pregnancy have not been studied in humans but testing in Guinea pigs resulted in fetal loss.