 As the highway approaches the community of Inwood, a diamond interchange with West Virginia Route 51 (WV 51) provides access to the community, as well as Gerrardstown to the west of the freeway, and Charles Town to the east.A small business park is passed by before I-81 intersects County Route 32 (CR 32), providing access to Arden, the Eastern WV Regional Airport and Tablers Station.The freeway turns more towards the north as it approaches Martinsburg, intersecting , CR 15 (King Street), and CR 13 (Dry Run Road) while in the city limits.