 The Steubenville and Indiana Railroad opened a line from Steubenville west to Newark in 1853, and 1854, and 1855.In 1857, it built a connection in Newark to the Central Ohio Railroad and signed a trackage rights agreement over the Central Ohio to Columbus; it bought a one-half interest in that portion of the Central Ohio in 1864.The Pennsylvania Railroad's Steubenville Extension, Pittsburg and Steubenville Railroad, and Steubenville Bridge across the Ohio River opened in 1865, connecting Pittsburgh to the Steubenville and Indiana.