 In 1524, Lappoli executed some frescoes, based on cartoons the latter had provided him, for a "Visitation" for Badia di Sante Fiore e Lucilla in 1524, an "Adoration of the Magi" for the church of San Francisco.In Rome, he was 
patronized by Clement VII, but he fled back to Arezzo with the Sack of Rome in 1527.He painted an "Allegory of Original Sin" in Montepulciano (1545).