 Nonetheless, in 1804, he was able to lead a small medical team which performed the colony's first successful vaccination of children against smallpox.He published Australia's first medical paper, "General Observations on the Smallpox", as a result of this experience.Another of Jamison's innovations occurred in 1808, when he and two colleagues undertook a formal examination of the medical competence of William Redfern, who was put forward by the gubernatorial authorities in Sydney as a person fit to perform surgery in the colony.