 The wife of Henry IV was Joan of Portugal, a Portuguese infanta daughter of King Edward of Portugal and his wife Eleanor of Aragon.The first wife of Rene died prior to 1462; his second wife was Jeanne de Laval, a French noblewoman and daughter Guy XIV de Laval, Count of Laval and Isabella of Brittany.In 1556, the union of the Spanish kingdoms is generally called Spain and Mary I of England (second wife of Philip II) is the first Queen of Spain.