 Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.Tetrandrine has also been shown to inhibit entry of Ebola virus into host cells "in vitro" and showed therapeutic efficacy against Ebola in preliminary studies on mice.Tetrandrine is biosynthesized from a free radical coupled dimerization of "S"-"N"-methylcoclaurine