 After crossing under Interstate 405 near the Verizon Wireless Amphitheater, the creek enters an artificial channel and receives Serrano Creek via an underground culvert on the right bank.Directly after the confluence, it passes under California State Route 133.It then flows northwest in a nearly straight course through East Irvine and the City of Irvine, receiving Agua Chinon Creek, Bee Canyon Wash, and the Marshburn Channel from the right.