 After attending the Second Vatican Council from 1962 to 1965, Salazar succeeded Anaya y Diez as Bishop of Zamora on September 15, 1967.He was later named Archbishop of Guadalajara on February 21, 1970.Pope Paul VI created him Cardinal Priest of "S. Emerenziana a Tor Fiorenza" in the consistory of March 5, 1973.