 As a poor man and a poor boy, I conceived the idea that whoever could produce a tasteless chill tonic, his fortune was made.” — E.W.Grove 
Grove’s Laxative Bromo Quinine, which was first produced in 1896, was an early cold tablet that combined quinine with other ingredients thought to relieve cold symptoms, including bromide (a sedative) and a laxative.Although complete contents of the original tablets were not revealed, later formulations contained (in addition to quinine and bromide) phenolphthalein as the laxative, an analgesic such as acetanilide or phenacetin, and medicinal plant extracts.