 Firstly, α-Dystrobrevin is a component of the dystrophin-glycoprotein complex, which is extremely useful for maintenance of the skeletal cell integrity.α-dystrobrevin associated with dystrophin at its coil-coil region and with a sarcoglycan-protein complex at the amino-terminal.It has been proposed to function as a structural scaffold linking the dystrophin-glycoprotein complex to the intracellular cytoskeleton.