 The pharmacokinetics of delorazepam are not altered if it is taken with food, except for some slowing of absorption.Delorazepams potency is approximately equal to that of lorazepam, being ten times more potent by weight than diazepam (1 mg delorazepam = 1 mg lorazepam = 10 mg diazepam), typical doses range from 0.5 mg - 2 mg.Treatment is generally initiated at 1 mg for healthy adults and 0.5 mg in pediatric and geriatric patients and patients with mild renal impairment, treatment is contraindicated in patients with moderate or severe renal impairment.