 It is thought to be involved in synaptic transmission at the neuromuscular junction and in intracellular signaling.The β-dystrobrevin, is only found in non-muscle tissues, predominantly expressed in kidney and brain, and forms complexes with dystrophin-associated proteins and syntrophin in liver and brain.In the brain, β-dystrobrevin associates with dystrophin isoforms in the cortex, hippocampus, and Purkinje neurons.