 Before obtaining his first tenure-track academic position, Chakraborty served as Research Scholar and Senior Research Fellow at the Indian Statistical Institute, Visiting Lecturer of Statistics at the Indian Institute of Management, and Visiting Consultant at the Data Reference Center of the World Health Organization at the University of Hawaii in Honolulu.In 1973, Chakraborty joined the faculty at the Center for Demographic and Population Genetics, which is now the Human Genetics Center, at the University of Texas Health Science Center at Houston.From 1996 to 2001, he held the Allan King Professorship at the School of Public Health.