 Mary Hayashi has worked for several non-profit and philanthropic organizations dedicated to healthcare issues including the American Public Health Association, the Foundation Consortium for California's Children and Youth, and the National Asian Women's Health Organization.In 2016 Mary Hayashi was appointed Project Director of the Women's Sport Safety Initiative, a special project fund of Silicon Valley Community Foundation dedicated to protecting the lives of women and girls by raising awareness of sports-related injuries.Mary Hayashi served as a member of the California Board of Registered Nursing and as Chair of the Planned Parenthood Golden Gate Political Action Committee.