 Most of the population is employed in the agricultural sector, with tobacco, corn and cotton being the main products.The population of Kalambaki consists mainly of descendants of four population groups, Pontus Greeks, Greeks of Eastern Thrace, Greeks of Asia Minor (mainly from Cappadocia, whose ancestors spoke Turkish but were Greek Orthodox Christians in religion) and Greeks whose ancestors had been living in Kalambaki already before the Treaty of Lausanne (1923) was ratified.In the vicinity of Kalambaki Roman milestones have been discovered indicating that the ancient Via Egnatia passed very close by.