 The A565 starts in Liverpool at the junction with the A5052 road and A5053 road respectively, at the south end of Great Howard Street; a spur also heads southbound from this junction for .From Liverpool, the road follows a north-bound alignment through Bootle, Crosby and on to Formby where it passes along a bypass.After the bypass, the road heads towards Southport where it meets the A570 Scarisbrick New Road before continuing north-east through Banks and into Lancashire, ultimately reaching Tarleton where it meets and becomes the A59 road.