 The ("R")- and ("S")-enantiomers have similar pharmacological action in animals.Armodafinil has wake-promoting actions similar to sympathomimetic agents including amphetamine and methylphenidate, although its pharmacologic profile is not identical to that of the sympathomimetic amines.Armodafinil is an indirect dopamine receptor agonist; it binds "in vitro" to the dopamine transporter (DAT) and inhibits dopamine reuptake.