 The ceiling is colorfully decorated with elaborate framed designs (cassetone) and has a central frescoed panel depicting the "Martyrdom of Anastasia" (1722) by Michelangelo Cerruti; the work was pursued under the patronage of the Cardinal Nuno Cardeal da Cunha e Ataíde.The presbytery was richly decorated in 1705 with marble by the Febei family rebuilt with an endowment of the cardinal Giambattista Costaguti.Under the main altar is said to sheltered the relics of the titular saint.