 "A. trichotis" has numerous threats, which most likely explains their low population size.Humans seem to have the largest impact on these mammals with acts such as deforestation, localized hunting and trapping for human consumption, and destruction of its rain forest habitat (primarily due to slash-and-burn agriculture).Because the species is extremely difficult to locate due to its similarity to "Microcebus rufus", distribution is recorded as being restricted and patchy with an overall low population density and the populations are rapidly declining in numbers due to rapid destruction of habitat.