 Its main uses are in breast cancer and malignant melanoma surgery, although it has been used in other tumor types (colon cancer) with a degree of success.Other cancers which have been investigated with this technique are penile cancer, urinary bladder cancer, prostate cancer, testicular cancer and renal cell cancer.As a bridge to translational medicine, various aspects of cancer dissemination can be studied using sentinel node detection and ensuing sentinel node biopsy.