 Likewise, physical exercise training interventions may have positive effects on physical fitness, including cardio-respiratory fitness, muscle strength and health-related quality of life.Adolescent and young adult (AYA) survivors, often defined as being between the ages of 15 and 39, have seen advancements in technology and modern medicine causing a dramatic increase in the number of AYA survivors.Prior to 1970, being diagnosed with cancer during childhood was considered a universally fatal disease.