 They commonly include fatigue, pain, sleep problems, physical side effects like lymphoedema, weight gain, anxiety and depression, fear of cancer recurrence, and impaired quality of life.If the treatment is lengthy and disruptive, many patients experience some difficulty in returning to normal daily life.The energy needed to cope with a rigorous treatment program may have caused them to disconnect from previous daily patterns, such as working, normal self-care, and housekeeping.