 He died in his Rome palace, the (Palazzo Madama, today the home of the Italian Senate) and was buried in the church of Sant'Urbano, Rome.The epitaph on De Monte's tomb describes him as an "excellent patron of the good arts".Del Monte was a perceptive supporter of the arts and sciences - he was the first recorded owner of the Portland Vase, and his Palazzo Madama household was one of the most important intellectual salons in Rome.