 For two years, the hospital provided medical treatment, mental reconditioning and vocational training for more than 4,000 afflicted soldiers returned from service with the American Expeditionary Forces in France.Carlisle Barracks' equipment laboratory designed and tested new products, including improved lighting for field hospitals, a field dental dispensary, first aid kits for arctic rescue, and the "First-aid Packet, U.S. Government Carlisle Model" bandage field dressing

In the fall of 1920, the Medical Field Service School was established under Colonel Percy M. Ashburn's command.Drawing on the lessons of World War I, the school developed medical equipment and doctrine suitable for the battlefield.