 The current church was rebuilt from 1585 to 1603 for a monastery of Cistercian nuns founded on the site in 1587, which still exists there.The church served as the national parish for residents of Rome from the United States from 1921 to 2017, during which period it was assigned to the care of the Paulist Fathers, a society of priests founded in the United States.About 280, an early Christian house of worship was established on this site, which, like many of the earliest Christian meeting places, was in a house ("domus ecclesiae").