 Speght published twice in her lifetime.Speght's writings include response essays, pamphlets, and pieces of poetry.At age 19, Speght published "A Mouzell for Melastomus" (London, 1617) (the title means "a muzzle for black mouth"), a prose refutation of Joseph Swetnam's misogynistic "The Araignment of Lewde, Idle, Froward, and Unconstant Women" (London, 1615).