 In 1438, during the war between the Republic of Venice and the Duchy of Milan, he intervened successfully to raise the siege of Brescia by Niccolò Piccinino, general to Filippo Maria Visconti, the Duke of Milan.Subsequently, he defended Brescia with 29 Bergamaschi soldiers.In the following years Scaramuccia remained loyal to the Serenissima, and in the summer of 1446 he fought against the Visconti's army at the head of 400 infantry.