 Both SLI , and CrossFire setups only allow up to four 8K (7680x4320) monitors, or eight 4K monitors (3840x2160).Each monitor requires its own dedicated graphics card (except for 4K, and standard HD), in that case up to two monitors can be on one dedicated graphics card.Major downside of CrossFire is that it works only in fullscreen mode, requiring extrinsic support for software or games when run in borderless/windowed mode.