 Pizarro remained with the Braves through 1960, compiling a 23–19 record and 3.93 ERA in Milwaukee.On December 15, 1960, he was traded with Joey Jay to the Cincinnati Reds for Roy McMillan, then immediately sent by the Reds with Cal McLish to the Chicago White Sox for Gene Freese.Pizarro enjoyed his greatest success as a member of the White Sox.