 Seay recorded his first Major League save for the Tigers on May 20, 2007 against the St. Louis Cardinals.In 2009, Seay tore his rotator cuff in his left shoulder, ending a solid season in which he compiled a 6–3 record and 4.25 ERA out of the Tigers bullpen.After spending all of 2010 trying to recover without surgery, Seay gave in and scheduled surgery.