 Bacteria that have some evidence of palytoxin or its analogue production include "Pseudomonas", "Brevibacterium", "Acinetobacter", "Bacillus cereus", "Vibrio" sp.ja "Aeromonas".The toxicity of palytoxin is due to its binding to external part of Na+/K+-ATPase (the sodium–potassium pump), where it interacts with the natural binding site of ouabain with very high affinity.