 Due to the fact that it was the only hospital in Brazil which was exclusively dedicated to these episodes, and, besides, since it was attached to a research and educational institution, Dr. Rosenfeld favored from the beginning the systematic observation of patients, resulting over the years in a large and original body of new knowledge about symptoms and treatment of victims of animal poisoning.This, in addition, spurred the realization of a large number of laboratory studies.Based on his experience in the field of hematology, Dr. Rosenfeld published many studies on the pathophysiology of snake bite poisoning in experimental animals, and was able to apply this rich knowledge to the clinical area.