 On the afternoon of October 6, 2004 after many years of health issues, Santiago died at the age of 56 at the San Pablo Hospital in Bayamón, Puerto Rico.His funeral was well attended by the public and music friends, with his brother Billyván playing a Plena tribute to Marvin.In the Villa Palmeras neighborhood in Santurce, there is a square named ""Plaza De Los Salseros"" honoring the memory of distinguished Salsa music luminaries.