 ESA's space flight programme includes human spaceflight (mainly through participation in the International Space Station programme); the launch and operation of uncrewed exploration missions to other planets and the Moon; Earth observation, science and telecommunication; designing launch vehicles; and maintaining a major spaceport, the Guiana Space Centre at Kourou, French Guiana.The main European launch vehicle Ariane 5 is operated through Arianespace with ESA sharing in the costs of launching and further developing this launch vehicle.The agency is also working with NASA to manufacture the Orion Spacecraft service module that will fly on the Space Launch System.