 For example, UCU, UCC, UCA and UCG are all serine, regardless of the third base.Active enzymatic deamination of cytosine or 5-methylcytosine by the APOBEC family of cytosine deaminases could have both beneficial and detrimental implications on various cellular processes as well as on organismal evolution.The implications of deamination on 5-hydroxymethylcytosine, on the other hand, remains less understood.