 In 1876, Dr. Cunningham accepted a call to the First Presbyterian Church of Wheeling, West Virginia.New work was found there with capable women ready to be organized for Christian labor, and for fifteen years, she was the president of a missionary society which included all the women and children of the thirty-nine churches in the Presbytery of Washington.For nearly ten years, she was one of the secretaries of the Chautauqua Missionary Institute, in which women of all denominations meet annually.