 Sharman worked at the University of Alabama at Birmingham as a member of international team of biomedical researchers on a US National Institutes of Health funded study of mucosal immunology and oral vaccine development (1991 – 1993).The main focus of his research was on experimental models of hapten-induced Inflammatory bowel disease and studying intraepithelial lymphocytes.Between 1994 and 2001, Sharman worked at International Demographic and Health Survey.