 The next week, he earned a career-high nine combined tackles as the 49ers lost to the Indianapolis Colts 23–26.On December 24, 2017, Johnson made his second career interception after picking off a pass attempt by Blake Bortles and returning it for a 50-yard touchdown during a 44-33 win over the Jacksonville Jaguars.Johnson led the Niners in tackles during the 2017 season, but despite this statistical output, he also struggled mightily in pass coverage, with Pro Football Focus giving him an overall grade of 36.9 on the season.