 Sera Khandro was born into a rich family, but ran away at the age of 14 to escape an unwanted engagement and to follow the Vajrayana teacher Drime Ozer, who was then in Lhasa on pilgrimage from Golok in Eastern TIbet.She returned with him and his followers to Golok, where she lived in poverty; there she became life partners with Garra Gyelse.Garra Gyelsel disliked her terma revelations, and this caused Sera Khandro to become sick.