 Following d'Entremont's article, Marion Nestle stated that d'Entremont's criticisms were "valid scientifically", and that "the difficulty with the kinds of compounds that Vani Hari has been dealing with is that they're present in the food supply in very small amounts, and therefore it's very hard to test whether small amounts are harmful or not harmful, so the science is uncertain, it's nuanced, it's very hard to talk about.