 "NF1" mRNA editing was believed to involve the ApoB holoenzyme due to the high homology between the two editing sites, however studies have shown that this is not the case.The editing site in "NF1" is longer than the sequence required for ApoB mediated mRNA editing, and the region contains two guanidines which are not present in the ApoB editing site.Mutations in "NF1" are primarily associated with neurofibromatosis type 1 (NF1, also known as von Recklinghausen syndrome).