 Later it was under the Aldobrandeschi family, who were followed by Orvieto, the Republic of Siena and the Orsini, who built the Castle.Conquered by the Spaniards in 1555. it was assigned to Cosimo I de' Medici as part of his new Grand Duchy of Tuscany.The city subsequently decayed and the area depopulated due to the presence of malaria.