 In 1373 Emperor Charles IV assigned it to the viscounts of Turrena, and later it was contended by several local barons such as the Corbara family and a nephew of Pope Sixtus IV.In 1481 it was returned to Orvieto.In 1643, during the War of Castro fought between the Barberini Pope Urban VIII and the house of Farnese, Monteleone was besieged and destroyed by the troops of Florence.