 In addition to neurofibromatosis type I, mutations in "NF1" can also lead to juvenile myelomonocytic leukemias (JMML), gastrointestinal stromal tumors (GIST), Watson syndrome, astrocytic neoplasms, phaeochromocytomas and breast cancer.No effective therapy NF1 yet exists.Instead, people with neurofibromatosis are followed by a team of specialists to manage symptoms or complications.