 The editing site in "NF1" is longer than the sequence required for ApoB mediated mRNA editing, and the region contains two guanidines which are not present in the ApoB editing site.Mutations in "NF1" are primarily associated with neurofibromatosis type 1 (NF1, also known as von Recklinghausen syndrome).NF1 is the most common single gene disorder in humans, occurring in about 1 in 2500-3000 births worldwide.