 John Ashburnham, 1st Baron Ashburnham, a landowner and politician, died at Southampton Street on 21 January 1710, aged 54.Charles Combe, the physician and numismatist, was born on 23 September 1743 in Southampton Street, where his father, John Combe, had a business as an apothecary.Sir William Schwenck Gilbert, the dramatist, librettist, poet, and illustrator, who collaborated with the composer Sir Arthur Sullivan in the Gilbert and Sullivan partnership, was born at 17 Southampton Street on 18 November 1836.