 Maria Eufrosyne gave birth to eleven children, of whom only three survived their own parents.These three were Privy Councillor Gustaf Adolf (1647–95), Catharina Charlotta (1655–97, wife of Field Marshal Otto Wilhelm Königsmarck) and Hedvig Ebba (c. 1659 – 1700, wife of Count Carl Gustaf Eriksson Oxenstierna).During his life, De la Gardie succeeded in adding large numbers of estates and castles to his possession.