 This segment overlapped a formerly well-traveled Native American removal route from Springfield, Missouri to Fayetteville from the 1830s.John Butterfield built a hotel and several barns in Fayetteville for his travelers to utilize before continuing north to Fitzgerald Station in Shiloh, Mudtown, Cross Hollows, Callahan's tavern and Missouri.Today, the route has been partially preserved as Arkansas Highway 265 in Northwest Arkansas and (partially) as Old Wire Road in Fayetteville.