 Almost identical sequences can be found across the animal kingdom, meaning that toolkit genes such as "Hox" must have evolved before the Cambrian radiation which created most of the animal body plans that exist today.These genes are used and reused, occasionally by duplication but far more often by being applied unchanged to new functions.Thus the same signal may be given at a different time in development, in a different part of the embryo, creating a different effect on the adult body.