 Following a failed campaign for the office of Missouri State Treasurer in 2004, Klumb ran for the 10th District Missouri State Senate seat vacated by Charles Wheeler in 2006.Klumb lost the Democratic primary in August 2006 to Jolie Justus.Jason Klumb was appointed by President Obama to the position of Regional Administrator of The Heartland Region for the U.S. General Services Administration on February 24, 2010.