 On 27 March 2008, Mifsud scored five goals for Malta in a 7–1 friendly win over Liechtenstein, completing a hat-trick within just 21 minutes of the kickoff.On 3 March 2010, he surpassed Carmel Busuttil's goalscoring record with the national team, as Mifsud hit the back of the net for Malta in an exhibition match against Finland, which finished in a 1–2 loss for the locals.Mifsud also scored the winning goal (1–0) in Malta's first away win in a World Cup qualifier in many years, against Armenia, on 7 June 2013.