 In addition to its role as a classical transcription factor, "N-myc" may recruit histone acetyltransferases (HATs).This allows it to regulate global chromatin structure via histone acetylation.The "Myc" family was first established after discovery of homology between an oncogene carried by the Avian virus, Myelocytomatosis ("v-myc"; ) and a human gene over-expressed in various cancers, cellular Myc ("c-Myc").