 The margins will become better defined with time with a narrow rim of congestion attributable to inflammation at the edge of the lesion.Relatively few extravasated red cells are lysed so the resulting hemosiderosis is limited and results in a progressively more pale area of infarction with time.Ischemic coagulative necrosis results and fibrosis of the affected area develops from the reparative response beginning at the preserved margins and working its way inwards.