 Manupuna played college football at the University of Colorado and started in all 13 games as a senior, including the Champs Sports Bowl.He enjoyed his best season as a senior where he earned honorable mention All-Big 12 Conference honors from both the Associated Press and the league coaches.Manupuna had 52 total tackles on his senior season (28 solo), including four for losses, five third down stops, seven quarterback hurries, two fumble recoveries and two pass breakups.