 She sang on a number of radio programs during her career, including "The American Album of Familiar Music", "The American Melody Hour", and "The Standard Hour" among others.A particularly important triumph for her radio career was a 1943 radio concert of Brahms’s "Deutsches Requiem" with conductor Arturo Toscanini and the NBC Symphony Orchestra.In addition to her radio career, Della Chiesa performed actively on the opera stage, mostly at the Chicago City Opera Company and the Chicago Opera Company, during the 1930s and 1940s.