 This state leads to inhibition and thus are their inhibitory interneurons that modulate this shift and if so are inhibitory neurotransmitters such as GABA involved?Lastly, neurons capable of modulating gates such as hippocampal and thalamic neurons can contact many different areas of the brain.With increasing research saying that neurons in the cortex, nucleus accumbens, and cerebellum are all able to be gated, can the hippocampus modulate the signals for all of these and if so can it connect these different brain areas into a much larger neural network capable of being modulated all at once?