 One story, "The Girl Had Guts", by Theodore Sturgeon, involved an alien virus that caused its victims to vomit up their intestines; Ashley records a reviewer saying that the story made him physically ill.

Ed Emshwiller supplied eight of the ten covers; he had sold several covers to "F&SF" by this time, so his work reinforced the sense of connection between the two magazines.Emshwiller also contributed interior illustrations in the first issue, but the main interior artist was John Giunta, with John Schoenherr contributing some of his earliest work to several of the later issues.Some well-known writers appeared during this incarnation of "Venture", including Isaac Asimov, Clifford Simak, Marion Zimmer Bradley, Robert Silverberg, and Damon Knight.