 's use of one-pot operations allowed them to perform several reactions steps in a single pot, which ultimately minimized the number of purification steps needed, waste, and saved time.In the first one-pot operation, Hayashi et al.begins by using diphenylprolinol silyl ether (4) as an organocatalyst, along with alkoxyaldehyde (2) and nitroalkene (3) to perform an asymmetric Michael reaction, affording an enantioselective Michael adduct.