 The brilliant palette ought to have been expected by the restorers as the same range of colours appears in the works of Giotto, Masaccio and Masolino, Fra Angelico and Piero della Francesca, as well as Ghirlandaio himself and later fresco painters such as Annibale Carracci and Tiepolo.The reason for employing this range of colours is that many other pigments are not usable in fresco as they have chemical properties that react badly in interaction with wet plaster.The colour that is noticeably missing from Michelangelo's ceiling, but not "The Last Judgment", is the intense blue of lapis lazuli.