GM cotton crop was 4.0 million hectares in 2011 the second largest area in the world, the Chinese GM cotton crop was third largest by area with 3.9 million hectares and Pakistan had the fourth largest GM cotton crop area of 2.6 million hectares in 2011. The initial introduction of GM cotton proved to be a success in Australia – the yields were equivalent to the non-transgenic varieties and the crop used much less pesticide to produce (85% reduction). The subsequent introduction of a second variety of GM cotton led to increases in GM cotton production until 95% of the Australian cotton crop was GM in 2009 making Australia the country with the fifth largest GM cotton crop in the world. Other GM cotton growing countries in 2011 were Argentina, Myanmar, Burkina Faso, Brazil, Mexico, Colombia, South Africa and Costa Rica. Cotton has been genetically modified for resistance to glyphosate a broad-spectrum herbicide discovered by Monsanto which also sells some of the Bt cotton seeds to farmers. There are also a number of other cotton seed companies selling GM cotton around the world. About 62% of the GM cotton grown from 1996 to 2011 was insect resistant, 24% stacked product and 14% herbicide resistant. Cotton has gossypol, a toxin that makes it inedible. However, scientists have silenced the gene that produces the toxin, making it a potential food crop. On 17 October 2018, the USDA deregulated GE low-gossypol cotton. Organic production Organic cotton is generally understood as cotton from plants not genetically modified and that is certified to be grown without the use of any synthetic agricultural chemicals, such as fertilizers or pesticides. Its production also promotes and enhances biodiversity and biological cycles. In the United States, organic cotton plantations are required to enforce the National Organic Program (NOP). This institution determines the allowed practices for pest control, growing, fertilizing, and handling of organic crops. As of 2007, 265,517 bales of organic cotton were produced in 24 countries, and worldwide production was growing at a rate of more than 50% per year. Organic cotton products are now available for purchase at limited locations. These are popular for baby clothes and diapers; natural cotton products are known to be both sustainable and hypoallergenic. Pests and weeds The cotton industry relies heavily on chemicals, such as fertilizers, insecticides and herbicides, although a very small number of farmers are moving toward an organic