religious leader of the Protestants throughout Mary's reign. In several interviews with the Queen, Knox admonished her for supporting Catholic practices. After she was imprisoned for her alleged role in the murder of her husband Lord Darnley, and King James VI was enthroned in her stead, Knox openly called for her execution. He continued to preach until his final days. Early life, 1505–1546 John Knox was born sometime between 1505 and 1515 in or near Haddington, the county town of East Lothian. His father, William Knox, was a merchant. All that is known of his mother is that her maiden name was Sinclair and that she died when John Knox was a child. Their eldest son, William, carried on his father's business, which helped in Knox's international communications. Knox was probably educated at the grammar school in Haddington. At this time, the priesthood was the only path for those whose inclinations were academic rather than mercantile or agricultural. He proceeded to further studies at the University of St Andrews or possibly at the University of Glasgow. He studied under John Major, one of the greatest scholars of the time. Knox was ordained a Catholic priest in Edinburgh on Easter Eve of 1536 by William Chisholm, Bishop of Dunblane. Knox first appears in public records as a priest and a notary in 1540. He was still serving in these capacities as late as 1543 when he described himself as a "minister of the sacred altar in the diocese of St. Andrews, notary by apostolic authority" in a notarial deed dated 27 March. Rather than taking up parochial duties in a parish, he became tutor to two sons of Hugh Douglas of Longniddry. He also taught the son of John Cockburn of Ormiston. Both of these lairds had embraced the new religious ideas of the Reformation. Embracing the Protestant Reformation, 1546–1547 Knox did not record when or how he was converted to the Protestant faith, but perhaps the key formative influences on Knox were Patrick Hamilton and George Wishart. Wishart was a reformer who had fled Scotland in 1538 to escape punishment for heresy. He first moved to England, where in Bristol he preached against the veneration of the Virgin Mary. He was forced to make a public recantation and was burned in effigy at the Church of St Nicholas as a sign of his abjuration. He then took refuge in Germany