Cove of Cork, Ireland for New York. July 10 – Vellore Mutiny: Indian sepoys mutiny against the East India Company, for the first time. July 12 – Sixteen German Imperial States leave the Holy Roman Empire and form the Confederation of the Rhine, leading to the collapse of the Empire after 844 years. Liechtenstein is given full sovereignty. July 15 – Pike Expedition: Near St. Louis, Missouri, United States Army Lieutenant Zebulon Pike leads an expedition from Fort Bellefontaine, to explore the American West. July 18 – 1806 Birgu polverista explosion: A gunpowder magazine explosion in Birgu, Malta kills around 200 people. July 23 – British invasions of the River Plate: A British expeditionary force of 1,700 men lands on the left bank of the Río de la Plata and invades Buenos Aires. August 6 – Francis II, the last Holy Roman Emperor, abdicates, thus ending the Holy Roman Empire after about a millennium. August 18 – English seal hunter Abraham Bristow discovers the Auckland Islands. September 23 – The Lewis and Clark Expedition reaches St. Louis, Missouri, ending a successful exploration of the Louisiana Territory and the Pacific Northwest. According to one historian, their arrival comes "much to the amazement of residents, who had given the travelers up for dead." September 25 – Prussia issues an ultimatum to Paris, threatening war if France does not halt marching its troops through Prussian territory to reach Austria; the message does not reach Napoleon Bonaparte until October 7, and he responds by attacking Prussia. October–December October 8 – Napoleon responds to the September 25 ultimatum from Prussia, and begins the War of the Fourth Coalition; Prussia is joined by Saxony and other minor German states. October 9 – Battle of Schleiz: French and Prussian forces fight for the first time since the war began. The Prussian army is easily defeated by a more numerous French force. October 14 – Battle of Jena–Auerstedt: Napoleon defeats the Prussian army of Prince Hohenlohe at Jena, while Marshal Davout defeats the main Prussian army under Charles William Ferdinand, Duke of Brunswick-Wolfenbüttel, who is killed. October 17 – Emperor Jacques I of Haiti (Jean-Jacques Dessalines) is assassinated at the Pont-Rouge, Haiti, and Alexandre Pétion becomes first President of the Republic of Haiti. October 24 – French forces enter Berlin. October 20 – British ship of the line is wrecked in the Strait of Sicily with the loss