Morley, similarly assumed the painting was meant to be a satire of rural small-town life. It was thus seen as part of the trend toward increasingly critical depictions of rural America along the lines of, in literature, Sherwood Anderson's 1919 novel Winesburg, Ohio, Sinclair Lewis's 1920 Main Street, and Carl Van Vechten's 1924 The Tattooed Countess. However, with the deepening of the Great Depression not too long after the painting was made, American Gothic came to be seen as a depiction of the steadfast American pioneer spirit. Wood assisted this interpretive transition by renouncing his bohemian youth in Paris and grouping himself with populist Midwestern painters such as John Steuart Curry and Thomas Hart Benton, who revolted against the dominance of East Coast art circles. Wood was quoted in this period as stating, "All the good ideas I've ever had came to me while I was milking a cow." American art historian Wanda M. Corn insists that Wood was not painting a modern couple, but rather one of the past, pointing to the fact that Wood directed the models to wear old-fashioned clothing which he found inspiration for by consulting his family photo album. Wood even posed the figures in a way that resembled long-exposure photographs of Midwestern families that dated before World War I. Art historian Tripp Evans interpreted it in 2010 as an "old-fashioned mourning portrait ... Tellingly, the curtains hanging in the windows of the house, both upstairs and down, are pulled closed in the middle of the day, a mourning custom in Victorian America. The woman wears a black dress beneath her apron, and glances away as if holding back tears. One imagines she is grieving for the man beside her.” Wood had been only 10 when his father died, and later he lived for a decade "above a garage reserved for hearses", so death was probably on his mind. In 2019, culture writer Kelly Grovier described the painting as a portrait of Pluto and Proserpina, the Roman gods of the underworld (a comparison made earlier by American writer Guy Davenport in his analysis of the painting in a 1978 lecture, “The Geography of the Imagination” .) Grovier suggests the small globe on the weather vane at the very top of the painting represents the dwarf planet Pluto (the planet was famously discovered in 1930 around the time of the painting's creation). Grovier interprets the pitchfork-wielding