of disease-modifying antirheumatic drugs (DMARDs) family of medications. It is unclear exactly how it works. Mesalazine is claimed to be a PPAR-γ agonist. Mechanism of action Exact mechanism of mesalazine is unknown, but is speculated that mesalazine decreases synthesis of prostaglandin and leukotriene, modulating the inflammatory response derived from the cyclooxygenase and lipooxygenase pathways. It appears to act locally on colonic mucosa. Society and culture Brand names Mesalazine is sold under various names including Apriso, Asacol, Asacol HD, Canasa, Delzicol, Fivasa, Lialda, Pentasa, Rowasa, and Sfrowasa. References External links Anilines Anti-inflammatory agents Antioxidants Gastroenterology Salicylic acids AbbVie brands Takeda Pharmaceutical Company brands Wikipedia medicine articles ready to translate