and even routes running east–west. Primary routes have a one- or two-digit number, and are supplemented by spur routes that add a hundreds digit to their parent route. Routes increase from east-to-west and north-to-south, such that U.S. Route 1 follows the Atlantic Seaboard fall line, while U.S. Route 101 does the same at the Pacific Ocean Coast. Likewise U.S. Route 2 runs near the Canadian border, while U.S. Route 98 follows the Gulf Coast. Major cross-country routes end in either a "1" or a "0". For example, U.S. Route 20 is a route that runs over from Boston, Massachusetts, to Newport, Oregon, while U.S. Route 41 spans the country from Miami, Florida, to the Upper Peninsula of Michigan. Routes like U.S. Route 141 and U.S. Route 441 branch off U.S. Route 41. U.S. Route 66, known as the "Mother Road", was a cultural touchstone that inspired literature, songs, and other media from its creation in 1926 until it was superseded by segments of the Interstate Highway System. Parts of the road have been designated "Historic Route 66". The Interstate Highway System, indicated by a red and blue shield with white numbers, is a system of entirely freeways (unlike the U.S. Highway System, which is mostly undivided surface roads). The Interstate System is also based on a grid, with east–west routes bearing even numbers and north–south routes bearing odd numbers. In order to prevent confusion with the earlier U.S. Highway System, however, the Interstates are numbered in the opposite direction, such that the lowest routes numbers are in the south and west, and the highest numbers in the north and east. Major routes end in either a "0" or a "5"; for example Interstate 10 spans the country from Jacksonville, Florida, to Santa Monica, California, while Interstate 35 goes from the Mexican border to the Great Lakes. Like with U.S. Highways, subsidiary routes are numbered by adding a hundreds digit to the parent route. Because of the large number of these routes, three-digit numbers may be repeated within the system, but unique to each state. Additionally, the parity of the hundreds digit tells the nature of the spur route: odd hundreds digits like Interstate 393 only connect to the system at one end (forming "spurs"), while an even hundreds digit like Interstate 440 indicates that the highway connects to another Interstate at both ends (forming loops). The numbering system for state