Sancti-Spiritus is a municipality in the province of Salamanca, in the autonomous community of Castile-Leon, Spain. It is 70 km away from Salamanca, the capital of the province. It is situated 756 m above the sea level. The area of the municipality is 142 km² and it ranks 4th among the municipalities in the provinces of Salamanca after Ciudad Rodrigo, Castillejo de Martín Viejo, and Ledesma. As of 2016 its population is 854 inhabitants and the postal code 37470. References Municipalities in the Province of Salamanca