and he moved on to the Charisma Records offshoot Pre, who released his The Lonely Lover and More Gregory albums along with a string of increasingly successful singles including "Tune In", "Permanent Lover", "Wailing Rudie" and "Tribute to Waddy". He signed to Island Records and released the record that broke through to a wider audience, "Night Nurse", the title track from his first album for the label (Night Nurse (1982)). Although "Night Nurse" was not a chart hit in either the UK or US, it was popular in clubs and received heavy radio play, and the album reached number 32 in the UK. It was also used in adverts for an over the counter cold & flu remedy of the same name. This success for Isaacs coincided with drug problems with cocaine. He served a six-month prison sentence in Kingston in 1982 for possession of unlicensed firearms. Isaacs claimed that he had the weapons only for protection, but it emerged that this was his 27th arrest and that he had become involved in drug dealing and was addicted to crack cocaine. He celebrated his release from prison with his second album for Island, Out Deh! (1983). Yellowman wrote the song Gregory Free also celebrating Isaacs release, and was later featured on the Young, Gifted and Yellow album. He was featured in the 1982 documentary Land of Look Behind. When his contract with Island ended, Isaacs returned in 1984 with the "Kool Ruler Come Again" single, and began a period of prolific recording, working with producers including Prince Jammy, Hugh "Redman" James, Bobby Digital, Tad Dawkins and Steely & Clevie, maintaining a consistent standard despite the volume of work produced. Isaacs then built a strong relationship with Gussie Clarke of the Music Works label. They began with Isaacs's 1985 album Private Beach Party, and had a hit with "Rumours" in 1988, which was followed by further popular singles including "Mind Yu Dis", "Rough Neck", "Too Good To Be True" and "Report to Me". The association with Clarke continued into the early 1990s, teaming up with singers including Freddie McGregor, Ninjaman and J.C. Lodge. He dueted with Beres Hammond on the 1993 Philip "Fatis" Burrell-produced "One Good Turn", Burrell also producing Isaacs's 1994 album Midnight Confidential. In the 1990s, the African Museum label continued to release all of Isaacs's music, and that of artists he produced. In 1997 Simply Red covered "Night