of Sports Night, she gave birth to her first child and soon returned to work. In 2001, she starred on the not picked up CBS pilot Heart Department In 2003, she starred in Showtime's miniseries Out of Order. In 1999, she appeared in the Paul Thomas Anderson's ensemble drama Magnolia and television adaptation of 1938 movie A Slight Case of Murder along with William H. Macy. In 2002 she played Lady Bird Johnson in the HBO award-winning movie Path to War and made a cameo appearance in Door to Door, which starred, and was written by, her husband. She also starred in Snap Decision (2001) with Mare Winningham, Raising Helen (2004) as Kate Hudson's character's older sister, and Christmas with the Kranks (2004), as the best friend of Jamie Lee Curtis's character. 2004–2012: Desperate Housewives and Transamerica After a recurring role on the NBC sitcom Frasier, Huffman landed a leading role in an ABC comedy series Desperate Housewives, co-starring with Marcia Cross, Teri Hatcher, and Eva Longoria. Huffman won an Emmy Award for her work on Desperate Housewives (Outstanding Lead Actress in a Comedy Series) in 2005, as well as two 2006 Screen Actors Guild Awards (Best Actress - Comedy Series and part of Best Ensemble - Comedy Series) in 2006 and received several other awards. A report in November 2010 suggested that Huffman, along with co-star Teri Hatcher, would be quitting Desperate Housewives, but ABC denied the claim. The series ended in May 2012, after eight seasons. In 2005, Huffman starred in the independent drama Transamerica, playing Bree, a pre-operative transgender woman who, on the brink of her transforming surgery, discovered that in her youth she had fathered a son - who is now a troubled teen hustler on the run. Huffman's performance in Transamerica was praised by many critics and garnered her a Golden Globe Award for Best Actress, as well as nominations for Best Actress (Screen Actors Guild) and Best Actress (Academy Awards), and several other awards and nominations. Huffman is now a voting member of the Academy of Motion Picture Arts and Sciences. In 2007, Huffman starred in Garry Marshall's Georgia Rule with Jane Fonda and Lindsay Lohan, and 2008 on independent drama Phoebe in Wonderland. She made a film, Lesster, as a writer, director and actress in 2010. 2013–present: Subsequent career and American Crime Huffman said that after seeing her as Lynette Scavo on Housewives