ingestion has shown favorable long-term results with protective effects in myelinosis and brain damage. Limitations noted to be undesirable taste and is contraindicated in people with cirrhosis to avoid initiation or potentiation of hepatic encephalopathy. Conivaptan – an antagonist of both V1A and V2 vasopressin receptors. Tolvaptan – an antagonist of the V2 vasopressin receptor. Raising the serum sodium concentration too rapidly may cause central pontine myelinolysis. Avoid correction by more than 12 mEq/L/day. Initial treatment with hypertonic saline may abruptly lead to a rapid dilute diuresis and fall in ADH. Epidemiology The incidence of SIADH rises with increasing age. Residents of nursing homes are at highest risk. History The condition was first described at separate institutions by William Schwartz and Frederic Bartter in two people with lung cancer. Criteria were developed by Schwartz and Bartter in 1967 and have remained unchanged since then. Society and culture The condition is occasionally referred to by the names of the authors of the first report: Schwartz-Bartter syndrome. Because not all people with this syndrome have elevated levels of vasopressin, the term "syndrome of inappropriate antidiuresis" (SIAD) has been proposed as a more accurate description of this condition. References External links Pituitary disorders Syndromes Oncological emergencies Articles containing video clips