TCAs. Since the 1990s, it has no longer been used as commonly, but is sometimes still prescribed as a second-line treatment for treating major depression . It has also seen limited use in the treatment of migraines, ADHD, and post-concussive syndrome. Imipramine has additional indications for the treatment of panic attacks, chronic pain, and Kleine-Levin syndrome. In pediatric patients, it is relatively frequently used to treat pavor nocturnus and nocturnal enuresis. Society and culture Generic names Imipramine is the English and French generic name of the drug and its , , and , while imipramine hydrochloride is its , , , and . Its generic name in Spanish and Italian and its are imipramina, in German is imipramin, and in Latin is imipraminum. The embonate salt is known as imipramine pamoate. Brand names Imipramine is marketed throughout the world mainly under the brand name Tofranil. Imipramine pamoate is marketed under the brand name Tofranil-PM for intramuscular injection. Availability Imipramine is available for medical use widely throughout the world, including in the United States, the United Kingdom, elsewhere in Europe, India, Brazil, South Africa, Australia, and New Zealand. Prescription trends Between 1998 and 2017, along with amitriptyline, imipramine was the most commonly prescribed first antidepressant for children aged 5-11 years in England. References Further reading External links Alpha-1 blockers CYP2D6 inhibitors D2 antagonists Dibenzazepines Dimethylamino compounds Glycine receptor antagonists H1 receptor antagonists Muscarinic antagonists Nicotinic antagonists Novartis brands Serotonin receptor antagonists Serotonin–norepinephrine reuptake inhibitors Tricyclic antidepressants