hantaviruses are rarely spread that way. However, infection via human contact has been suggested in hantavirus outbreaks in Argentina. In 2004, microbiologist Edward McSweegan suggested the disease may have been an outbreak of anthrax poisoning. He hypothesized that the victims could have been infected with anthrax spores present in raw wool or infected animal carcasses, and suggested exhuming victims for testing. Numerous attempts have been made to define the disease origin by molecular biology methods, but have so far failed due to a lack of DNA or RNA. Epidemiology Fifteenth century Sweating sickness first came to the attention of physicians at the beginning of the reign of Henry VII, in 1485. It was frequently fatal; half the population perished in some areas. The Ricardian scholar John Ashdown-Hill conjectures that Richard III fell victim the night before the Battle of Bosworth Field and that this accounted for his sleepless night and excessive thirst in the early part of the battle. There is no definitive statement that the sickness was present in Henry Tudor's troops landing at Milford Haven. The battle's victor Henry VII arrived in London on 28 August, and the disease broke out there on 19 September 1485; it had killed several thousand people by its conclusion in late October that year. Among those killed were two lord mayors, six aldermen, and three sheriffs. Mass superstition and paranoia followed the new plague. The Battle of Bosworth Field ended the Wars of the Roses between the houses of Lancaster and York. Richard III, the final York king, was killed here and Henry VII was crowned. As chaos, grief, and anger spread, people searched for a culprit for the plague. English people started to believe it was sent by God to punish supporters of Henry VII. The sickness was regarded as being quite distinct from the Black Death, the pestilential fever, or other epidemics previously known because of its extremely rapid and fatal course, and the sweating which gave it its name. It reached Ireland in 1492, when the Annals of Ulster record the death of James Fleming, 7th Baron Slane from the pláigh allais ["perspiring plague"], newly come to Ireland. The Annals of Connacht also record this obituary, and the Annals of the Four Masters record "an unusual plague in Meath" of 24 hours' duration; people recovered if they survived it beyond that 24-hour period. It did not attack infants or