older aunts, with whom she had regular contact: Louise Hollandine of the Palatinate (a sister of her father and Abbess of Maubuisson since 1664) and Emilie of Hesse-Kassel (a sister of her mother, who had married the Huguenot general Henri Charles de La Trémoille, Prince of Taranto and Talmont). Children Liselotte and Philippe I of Orléans had three children together: Alexandre Louis d'Orléans, Duke of Valois (2 July 1673 – 16 March 1676). Born at the Château de Saint-Cloud and died at the Palais-Royal before his third birthday. His death has been attributed to bloodletting by the Orléans family's doctors; last person to carry the title Duke of Valois. Philippe d'Orléans (2 August 1674 – 2 December 1723). Born at the Château de Saint-Cloud, he was titled Duke of Chartres from birth until becoming Duke of Orléans in 1701; married his first cousin Françoise Marie de Bourbon and had issue; died at the Palace of Versailles; Regent of France and Navarre during the minority of Louis XV of France—the era was known as la Régence. Élisabeth Charlotte d'Orléans (13 September 1676 – 23 December 1744). Born at the Château de Saint-Cloud and married Leopold, Duke of Lorraine in 1698 and had issue; became the Sovereign Princess of Commercy 1737; she died at Commercy; known as Mademoiselle de Chartres, a title given her at birth; grandmother of Queen Marie Antoinette. Liselotte had a warm relationship with her children. She was devastated by the untimely death of her eldest son Alexandre Louis at the age of two. She mourned him for six months before the birth of her daughter, who apparently helped her over the terrible loss. Her younger son Philippe resembled her in appearance, and also shared her literary, artistic and scientific interests. During his father's lifetime and shortly thereafter, his relationship with his mother was distant under the influence of his father and his favorites, and his mother often criticized his debauchery. Later, however, their relationship improved. Difficulties and tragedies From around 1680 massive problems arose in the Orléans marriage, as the Chevalier de Lorraine, the Marquis d'Effiat and other favorites of her husband intrigued against Liselotte in order to eliminate her influence on the Duke. Among other things, her enemies conspired to have her confidantes, including her beloved lady-in-waiting Lydie de Théobon-Beuvron and her husband, the Chamberlain Count de Beuvron, dismissed from court. After these departures she was defenseless