Wisconsin . Charles Durkee (FS) . Ben C. Eastman (D) . James D. Doty (ID) Non-voting members . Henry H. Sibley . Richard H. Weightman (D) . Joseph Lane (D) . John M. Bernhisel Changes in membership The count below reflects changes from the beginning of the first session of this Congress. Senate Replacements: 8 Democrats (D): 1 seat net gain Whigs (W): 1 seat net loss Deaths: 3 Resignations: 6 Interim appointments: 3 Total seats with changes: 13 |- | Ohio(1) | Vacant | Failure to elect.The winner was elected late on March 15, 1851, on the 37th ballot over the incumbent appointee.Successor was elected March 15, 1851. | | Benjamin Wade (W) | Elected March 15, 1851 |- | New York(1) | Vacant | Failure to elect.Successor was elected March 19, 1851. | | Hamilton Fish (W) | Elected March 19, 1851 |- | Massachusetts(1) | Vacant | Failure to elect.Successor was elected April 24, 1851. | | Charles Sumner (FS) | Elected April 24, 1851 |- | California(1) | Vacant | Failure to elect.Successor was elected January 30, 1852. | | John B. Weller (D) | Elected January 30, 1852 |- | Connecticut(1) | Vacant | Failure to elect.Successor was elected May 12, 1852. | | Isaac Toucey (D) | Seated May 12, 1852 |- | Mississippi(1) | | Jefferson Davis (D) | Resigned September 23, 1851, to run for Governor of Mississippi.Successor appointed December 1, 1851. | | John J. McRae (D) | Appointed December 1, 1851 |- | Mississippi(2) | | Henry S. Foote (D) | Resigned January 8, 1852, to become Governor of Mississippi.Successor elected February 18, 1852. | | Walker Brooke (W) | Elected February 18, 1852 |- | Mississippi(1) | | John J. McRae (D) | Appointee was replaced by an elected successor.Successor elected March 17, 1852. | | Stephen Adams (D) | Elected March 17, 1852 |- | South Carolina(2) | | Robert Rhett (D) | Resigned May 7, 1852.Successor appointed May 10, 1852, and elected sometime thereafter to finish the term. | | William F. De Saussure (D) | Appointed May 10, 1852 |- | Georgia(2) | | John M. Berrien (W) | Resigned May 28, 1852.Successor appointed May 31, 1852, to finish the term. | | Robert M. Charlton (D) | Appointed May 31, 1852 |- | Kentucky(3) | | Henry Clay (W) | Died June 29, 1852.Successor appointed