Takes a Thief. This led to a recurring role playing a new character, Charlene "Chuck" Brown, Alexander Mundy's fellow thief and "casual" love interest. She was featured in four episodes of the series from 1968 to 1970. She went on to appear in the pilot episode of the western series Alias Smith and Jones (1971). Then came her first starring role as Rock Hudson's younger supportive wife, Sally McMillan, in the popular, light-hearted crime series, McMillan & Wife (1971–1976), for which she received four Emmy Award nominations. Saint James left the show due to a contract dispute but went on to further her career as an actress in feature films, such as co-starring with Peter Fonda in the film Outlaw Blues (1977). She achieved significant success in the vampire comedy Love at First Bite (1979) and followed up with a role in the comedy How to Beat the High Cost of Living (1980), co-starring Jessica Lange and Jane Curtin. Between films, she made a guest appearance in the March 3, 1980, episode of M*A*S*H (episode 192: "War Co-Respondent"). After other film ventures failed to establish her, she returned to television, starring in the comedy series Kate & Allie opposite Jane Curtin from 1984 until 1989. She received three more Emmy Award nominations for this role. Saint James was a celebrity guest commentator for the World Wrestling Federation's WrestleMania 2 event in 1986 along with Vince McMahon. In her mid-40s, Saint James retired after Kate & Allie ended. In addition to motherhood (her second-youngest son was born during the fourth season of Kate & Allie), she has been an active volunteer with the Special Olympics (an organization she began actively supporting in 1972) She has served on the Special Olympics board and was Civitan International's celebrity chairperson for their Special Olympics involvement. She also is a board member of the Telluride Foundation. In 1998, Saint James, her sister Mercedes Dewey and friend Barrie Johnson founded "Seedling and Pip", a baby gift basket business. Saint James occasionally has emerged from retirement to appear in television series guest roles, such as the mother of (her real-life niece) Christa Miller in the first season of The Drew Carey Show, and ten years later, as a defense attorney on the February 28, 2006, episode of Law & Order: Special Victims Unit. She also starred in a Warner Theatre (Torrington, Connecticut) 1999 production of The Miracle