a seventh-round knockout in a rematch with Caceres. On 19 February 1960, he fought Ernesto Miranda for the third time, this time with the South American Bantamweight title on the line. Jofre outpointed Miranda over fifteen rounds to win his first title as a professional. Jofre retained the title with a knockout in three rounds in the fourth fight with Miranda, and, after one more win, he made his U.S. debut, defeating top-ranked challenger Jose Medel by knockout in ten rounds on 16 August in Los Angeles. Next, he defeated the power-punching Ricardo Moreno (later ranked among boxing's all-time best punchers by Ring Magazine), by a knockout in the sixth round. On 18 November of that year, Jofre became world champion, when he knocked out Eloy Sanchez in six rounds, in Los Angeles, to claim the vacant WBA World Bantamweight title. Jofre proved to be a busy world champion, fighting top-notch fighters, both in title engagements and in non-title fights. From 1960 to 1965, he retained his title against Piero Rollo, Ramon Arias (in Caracas, Venezuela), Johnny Caldwell, Herman Marques, Jose Medel, Katsuyoshi Aoki (in Tokyo), Johnny Jamito (in Manila), and Bernardo Caraballo (in Bogotá, Colombia). In addition, he defeated such fighters as Billy Peacock, Sadao Yaoita, and Fernando Soto in non-title bouts. After the fight with Aoki, Jofre was also recognized as World Bantamweight Champion by the WBC, therefore, becoming the Undisputed World Champion. On 17 May 1965, his streak as an undefeated fighter was broken when he lost to "Fighting Harada" by a controversial fifteen-round split decision in Nagoya, Japan, to lose the world Bantamweight title. After losing to Harada by unanimous decision at a rematch held in Tokyo on 1 June 1966, Jofre retired. In 1969, he made a comeback, beating Rudy Corona by a knockout in six rounds on 26 August. After winning thirteen fights in a row, he challenged for a world title once again: on 5 May 1973, he fought Jose Legra for the Lineal and WBC featherweight titles, in Brasilia. Jofre became a two-division world champion by defeating Legra with a fifteen-round majority decision. Despite having won his second world title, Jofre realized he was nearing the end of the road as far as his boxing career was concerned. He defeated Frankie Crawford in a non-title affair and defended his world Featherweight title against fellow former world Bantamweight champion Vicente Saldivar of Mexico,