National Institutes of Health or NIH has created a nationwide consortium of small-molecule screening centers to produce innovative chemical tools for use in biological research. The Molecular Libraries Probe Production Centers Network, or MLPCN, performs HTS on assays provided by the research community, against a large library of small molecules maintained in a central molecule repository. See also Chemoproteomics Compound management DNA-encoded chemical library Drug discovery hit to lead Dual-flashlight plot High-content screening High throughput biology IC50 / EC50 Laboratory automation Reverse Pharmacology Synthetic genetic array Virtual high throughput screening Yeast two-hybrid screening References Further reading Zhang XHD (2011) "Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-scale RNAi Research, Cambridge University Press" Flow cytometry enables a high-throughput homogeneous fluorescent antibody-binding assay for cytotoxic T cell lytic granule exocytosis External links Open Screening Environment Setting up High-Throughput Screening Laboratory (Koppal, Lab Manager Magazine) Assay Guidance Manual (NIH, NCGC) OncoSignature High Throughput Screening Scientific techniques Pharmaceutics Drug discovery