Peet appeared with Diane Keaton, Jack Nicholson and Keanu Reeves in the romantic comedy Something's Gotta Give, directed by Nancy Meyers, playing an auctioneer, working for Christie's. The film was a critical darling and a major success at the box office, grossing US$125 million in North America. In her other 2003 film release, the psychological horror thriller Identity, Peet starred as a Las Vegas prostitute, alongside John Cusack, Ray Liotta and John Hawkes. Identity received critical acclaim and was a moderate commercial success. In 2004, Peet starred in The Whole Ten Yards, the sequel to The Whole Nine Yards. Unlike the first film, this production was critically panned and flopped at the box office. Established career (2005–2010) Her most significant film role in 2005 was that of a woman who becomes a successful photographer, opposite Ashton Kutcher, in the romantic comedy A Lot Like Love, which revolved around two people whose relationship slowly evolves from lust to friendship to romance over the course of seven years. While overall response was mixed, the Los Angeles Times found Peet to be "charming and charismatic without being cloying or artificial." In 2005, she also performed in the play This Is How It Goes, filling in for Marisa Tomei at the last minute after six days of rehearsal, and appeared in the Woody Allen's tragicomedy Melinda and Melinda and the thriller Syriana, which was based loosely on former Central Intelligence Agency agent Robert Baer and his memoirs of being an agent in the Middle East. In 2006, Peet acted on Neil Simon's Broadway production of Barefoot in the Park, followed by the romantic drama Griffin & Phoenix, a remake of the 1976 ABC TV movie, in which she portrayed a terminally ill woman living life to the fullest. The television series Studio 60 on the Sunset Strip, which premiered on NBC in late 2006, featured her as the recently hired president of entertainment programming, with Matthew Perry, with whom she had starred in The Whole Nine Yards and The Whole Ten Yards, and Sarah Paulson, with whom she previously worked in Jack & Jill. For her role, Peet received a Satellite Award nomination for Best Actress – Television Series Drama. Despite being a critical success, the series was cancelled after one season. Peet starred as an attorney who stays home to raise a new baby in the romantic comedy The Ex (2007), which went