States Department of Agriculture (USDA) and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. Adherence to the 3Rs Under the industry principles of the 3Rs, Labcorp Drug Development also uses alternative test methods beyond animal testing (in vivo), which includes in vitro testing, non-testing methods (in silico) and analytics. Welfare standards Labcorp Drug Development reports that it continues to improve animal welfare: “Three years before the European Commission issued its current regulations on animal habitats, we increased the size of the pens for primates living in our labs in Germany in order to provide them with a more comfortable setting.” Labcorp Drug Development also shares research on animal welfare topics, such as social housing of nonhuman primates. Labcorp Drug Development employees have published a Code of Respect for humane care of animals used in scientific research. Animal welfare issues Ebola virus In December 1989 a number of cynomolgus macaques (Macaca fascicularis) were imported from Mindanao Island in the Philippines with the Ebola virus to Covance's Hazleton Research Products' Primate Quarantine Unit in Reston, Virginia. The company was using monkeys there for research purposes, according to The Washington Post. The virus was confirmed in one monkey and suspected in others among a group of 100. In March 1996 two macaques that had been shipped to Hazleton in Alice, Texas, tested positive for the Ebola virus from a group of 100 obtained from the same supplier. The strains were not infectious to humans, and no human illnesses were reported. Münster, Germany In 2003 the British Union for the Abolition of Vivisection (BUAV) sent a German investigative journalist, Friedrich Mülln, into the Covance facility in Münster, Germany's largest primate-testing center, where he filmed undercover for five months. The footage was shown on German public television in December 2003. Nature reported that it showed animal keepers dancing with half-anaesthetized monkeys, making their heads move to the rhythm of the music. It also showed staff handling the monkeys roughly and shouting at them. The monkeys were seen living isolated in small wire cages with little or no natural light and no environmental enrichment, with high noise levels caused by staff shouting and playing the radio, and undergoing surgery with no post-operative care. In response, Covance maintained that clips showing different technicians working in different buildings had been edited together, resulting in a sequence of events that did not