with Interstate 65 (I-65), US 72 approaches Huntsville from the west. Part of this section has the local name University Drive. At an interchange with Memorial Parkway, the route turns northward briefly, joining the routes of US 231 and US 431, until it breaks off from the Parkway and heads eastward again. (This part is known to locals as "72 East" because it is east of the Parkway; it has no other name.) Northeast of downtown Huntsville, US 72 interchanges with I-565. I-565/US 72 Alt., part of Corridor V of the Appalachian Development Highway System, terminates at the interchange while US 72 takes over the freeway alignment, joining Corridor V. I-565 is mentioned as the eastbound route and SR 20 is mentioned as the westbound route. Signs for I-565 east at this interchange recently were changed to remove any mention of SR 20 east. Most of the US 72 portion of Corridor V is a four-lane divided expressway with at-grade intersections. Past Huntsville, US 72 follows several mountain valleys to Scottsboro. From Scottsboro, the route follows a northeasterly routing similar to that of the Tennessee River as it enters Tennessee for the second time. All of US 72 within Alabama is four lanes in width. Additionally, much of US 72 has been upgraded through northeast Alabama, with interchanges at the major state highways. Just west of Moores Mill Road in Huntsville, US 72 becomes limited access over Chapman Mountain. Throughout Alabama, US 72 is paired with unsigned State Route 2 (SR 2). The stretch of US 72 paralleling I-59 to the far northeast in between Scottsboro and South Pittsburg contains multiple freeway-style Interchanges. East Tennessee US 72 enters Tennessee for the second time just south of South Pittsburg. At South Pittsburg, Corridor V ends at an interchange with Interstate 24. US 64, concurrent with I-24 west of the exit, departs the expressway and forms an overlap with US 72 through Kimball to Jasper, where US 41 joins the concurrency. Just east of Jasper, the highways cross the Tennessee River on Nickajack Lake. The route then follows a cut in the Cumberland Plateau made by the Tennessee River to the western outskirts of Chattanooga, where it interchanges with I-24 once more. Just east of the interchange, US 11 joins the overlap. Together, US 11, US 41, US 64, and US 72 follow the bluffs on Lookout Mountain above the Tennessee River