in developing relationships with potential mentors worthy of trust for example, perhaps as part of interprofessional work in the referral pathway from an emergency department to a hospital ward, or as part of the process and work of building knowledge on whether the new practices, people, and things introduced into our lives are indeed accountable or worthy of investing confidence and trust in (as captured by the empirically grounded construct of 'Relational Integration' within Normalization Process Theory). This can be traced in neuroscience terms to the neurobiological structure and activity of a human brain. Some studies indicate that trust can be altered e.g. by the application of oxytocin. Social identity approach The social identity approach explains trust in strangers as a function of group-based stereotypes or in-group favoring behaviors based on salient group memberships. With regard to ingroup favoritism, people generally think well of strangers but expect better treatment from in-group members in comparison to out-group members. This greater expectation then translates into a higher propensity to trust an in-group rather than out-group member. It has been pointed out that it is only advantageous to form such expectations of an in-group stranger if they too know the group membership of the recipient. There is considerable empirical activity related to the social identity approach. Allocator studies have frequently been employed to understand group-based trust in strangers. They may be operationalized as unilateral or bilateral relationships of exchange. General social categories such as university affiliation, course majors, and even ad-hoc groups have been used to distinguish between in-group and out-group members. In unilateral studies of trust, the participant is asked to choose between envelopes containing money that was previously allocated by an in-group or out-group member. They have no prior or future opportunities for interaction, simulating Brewer's notion that group membership was sufficient in bringing about group-based trust and hence cooperation. Participants could expect an amount ranging from nothing to the maximum value an allocator could give out. Bilateral studies of trust have employed an investment game devised by Berg and colleagues where individuals choose to give a portion or none of their money to another. Any amount given would be tripled and the receiver would then decide whether they would return the favor by giving money back to the sender. Trusting behavior on the part of the sender and the eventual trustworthiness of the receiver was exemplified through the giving of