repercussions of transplantation are high, with the potential of diseases and viruses crossing over to humans from the transplantation. Close contacts are at risk for such infections. Monitoring of close relations may also be required to ensure that xenozoonosis is not occurring. The question then becomes: does the autonomy of the patient become limited based on the willingness or unwillingness of friends and family to give consent, and are the principles of confidentiality broken? The safety of public health is a factor to be considered. If there is any risk to the public at all for an outbreak from transplantation there must be procedures in place to protect the public. Not only does the recipient of the transplantation have to understand the risks and benefits, but society must also understand and consent to such an agreement. The Ethics Committee of the International Xenotransplantation Association points out one major ethical issue is the societal response to such a procedure. The assumption is that the recipient of the transplantation will be asked to undergo lifelong monitoring, which would deny the recipient the ability to terminate the monitoring at any time, which is in direct opposition of the Declaration of Helsinki and the US Code of Federal Regulations. In 2007, xenotransplantation was banned under ethical grounds in all countries but Argentina, Russia and New Zealand. Since then, the practice has only been carried out to treatment for diabetes type 1 to serve as a substitute for insulin injections. The application of the four bioethics principal is found to be everywhere because it is now standardized in the moral conducts of a laboratory. The four principles emphasize on the informed consent, the Hippocratic Oath to do no harm, apply one's skill to help others, and protecting the rights of others to quality care. Problems with xenotransplantation is that even though it has future medical benefits, it also has the serious risk of introducing and spreading the infectious diseases, into the human population. There have been guidelines that have been drafted by the government that have the purpose of forming the foundation of infectious disease surveillance. In the United Kingdom, the guideline that were introduced state that first, "the periodic provision of bodily samples that would then be archived for epidemiological purposes;" second, "post-mortem analysis in case of death, the storage of samples post-mortem, and the disclosure of this agreement to their family;" third, "refrain