A serapeum is a temple or other religious institution dedicated to the syncretic Greco-Egyptian deity Serapis, who combined aspects of Osiris and Apis in a humanized form that was accepted by the Ptolemaic Greeks of Alexandria. There were several such religious centers, each of which was a serapeion () or, in its Latinized form, a serapeum. An Egyptian name for the temple of Osiris-Apis ( , ) was Pr-Wsỉr-Ḥp "House of Osiris-Apis". Egyptian serapea Alexandria The Serapeum of Alexandria in the Ptolemaic Kingdom was an ancient Greek temple built by Ptolemy III Euergetes. There are also signs of Harpocrates. It has been referred to as the daughter of the Library of Alexandria. It existed until the end of the fourth century AD. Saqqara The Serapeum of Saqqara is located north west of the Pyramid of Djoser at Saqqara, a necropolis near Memphis in Lower Egypt. It was a burial place of the Apis, sacred bulls that were incarnations of Ptah. It was believed that the bulls became immortal after death as Osiris-Apis, a name shortened to Serapis in the Hellenic period. Canopus Another serapeum was located at Canopus, in the Nile Delta near Alexandria. This sanctuary, dedicated to Isis and her consort Serapis, became one of the most famous cult centers of the Ptolemaic Kingdom and Roman Egypt. Its festivals and rites were so popular that the site became an architectural model for sanctuaries to the Egyptian gods throughout the Roman Empire. At this Graeco-Roman site, a sacred temenos enclosed the temple dedicated to the gods, which was located behind a propylaea or peristyle court. Auxiliary shrines dedicated to other, less universal, Egyptian deities could be found here as well, including those dedicated to Anubis (Hermanubis), Hermes Trismegistus, the syncretism of Thoth and Hermes, Harpocrates, and others. Ritual complexes dedicated to Isis were often built around a well or a spring, which was meant to represent the miraculous annual inundation of the Nile. This was also the case in sanctuaries devoted to the Egyptian gods in Roman-era Delos, where a central basin provided the water element central in the rites of Isis. Serapea in Italy Regio tertia The Regio III within the city of Rome was named Isis et Serapis because it contained a temple dedicated to the two Egyptian deities. The structure, originally dedicated to Isis alone, was built by Quintus Caecilius Metellus Pius in the first half of