result is a chemically induced immunodeficiency. To counteract the promicin inhibitor, Dr. Burkhoff develops a serum containing Isabelle's pure promicin. This serum neutralizes the charge so the inhibitor is not able to cross membranes and can be flushed out of the body. Setting The 4400 is set in Seattle, Washington, United States, but actually filmed in the Vancouver, British Columbia, Canada, area. Settings include: Promise City: founded by Jordan Collier with the guidance of Kyle Baldwin. It is created as a haven for people who are promicin-positive (P-positives), and also serves as the base of Collier's movement to spread promicin to the world. Collier intends for Promise City to be a model for the future, and the first stage to creating "Heaven on Earth". Though the characters claim that the location is on the Duwamish River delta, the map used and the footage featuring Promise City makes it clear this is impossible. The commentary states that Promise City was shot in Vancouver on the Burrard Inlet below the Second Narrows Bridge. Haspel Corporation: a fictional company whose name is also abbreviated as HaspelCorp, Haspelcorp, or Haspel Corp. The corporation's name and logo are introduced in the last minute of the episode "Graduation Day", where it is also implied that its building possesses at least 24 floors. A private defense contracting company of which Dennis Ryland is an executive, Haspel Corporation is the only known manufacturer of promicin, which they had been getting by filtering the blood from Isabelle Tyler. In the book Welcome to Promise City, Haspel Corporation has been banished out of Promise City's limits. The filming location used for HaspelCorp is the Life Sciences Centre at the University of British Columbia. It is home to the university's Life Sciences Institute and one of the medical research facilities on campus. The 4400 Center: a fictional building founded by Jordan Collier between the first and second seasons as a place where 4400s could take sanctuary and learn to harness their abilities, and where non-4400s could seek out the "inner" 4400 in themselves. A side effect of non-4400s joining the scheme was that they brought a great deal of money into the center. When Jordan was assassinated, Shawn Farrell (Jordan's "protégé") took over the operation of the center. Characters in the show sometimes call the 4400 Center a cult. The center was closed down and seized by the government in the