M-49 is a north–south state trunkline highway in the south-central portion of the US state of Michigan. It runs from the Ohio state line north to Litchfield through rural Hillsdale County. M-49 is the only Michigan highway in which the road crossing into another state has the same state highway number. M-49 continues as State Route 49 (SR 49), near the Indiana–Michigan–Ohio tripoint south of Camden. The highway dates back to 1930 and was only altered once in the 1940s. M-49 runs through Southern Michigan farmlands connecting several small towns along its path. At one point, M-49 briefly runs concurrently with US Highway 12 (US 12). Route description M-49 starts as the continuation of SR 49 into Michigan from Ohio. The highway crosses the state line south of Camden east of the tripoint with Indiana and Ohio. Running north through rural Hillsdale County, the roadway follows Edon Road through farm land. The highway follows two sweeping curves to cross Territorial Road and continue into the village of Camden. M-49 follows Main Street through town and turns northeasterly on the north side of the village on the way to Reading. Returning to a due-north course, the highway crosses a branch of the Indiana Northeastern Railroad on the south side of Reading. The Edon Road name gives way to Main Street through the city. M-49 runs north out of Reading, once again called Edon Road, through farm lands dotted with occasional trees. At Weston Road on the southeast side of Allen, the highway turns to the northeast to a junction with US 12 (Chicago Road). M-49 turns west along US 12, running concurrently into the village. M-49 resumes its northerly course at Railroad Street, separating from US 12 in the process. Outside of town, the roadway changes names to Allen Road, and through more Southern Michigan farmland, M-49 runs north to Genesee Road. The highway turns east on Genesee to Anderson Road, and then north to Litchfield. Crossing into that city, M-49 follows Chicago Street to the intersection with M-99 downtown. At that junction, M-49 terminates nearly north of the state line. No part of the highway has been listed on the National Highway System, a system of highways important to the nation's economy, defense, and mobility. History M-49 was added to the state highway system in 1930, running along its current routing between M-9 (now M-99) in Litchfield and the Ohio