Kelly was the founding member of the International Pediatric Transplant Association (IPTA) and served as its vice president from 1998 to 2002 and President from 2002 to 2005. She was the President of the British Society of Paediatric Gastroenterology & Hepatology (2004–07) and the European Society of Paediatric Gastroenterology & Hepatology (2007–10). She is the Chairperson of the Public Affairs Committee at the European Society of Paediatric Gastroenterology Hepatology Nutrition since 2017. She is the Clinical Lead for the National Paediatric Hepatitis C Operational Delivery Network at NHSE since 2021. She has been a deputy lieutenant of the West Midlands since 2008. Research Kelly has authored numerous publications including articles in peer-reviewed journals. Her research interests lie in the fields of the genetics of neonatal liver disease, management and treatment of pediatric liver disease, particularly focusing on auto-immune liver disease, viral hepatitis biliary atresia, cholestatic liver disease and the long term outcome following liver transplantation. Biliary atresia Kelly conducted research on pediatric hepatic diseases with a particular focus on biliary atresia. She advocated centralizing the Kasai Portoenterostomy (a surgical procedure) for the treatment of Biliary Atresia in infants, citing its ability to greatly enhance bile drainage along with keeping serum bilirubin levels within range, thus improving the patient's quality of life. She was also part of the team that analyzed the handling of Biliary Atresia patients in England and Wales from 1999 to 2002 in supra-regional centers. The study involved 148 infants and the results showed that out of 96% of the infants that underwent kasai portoenterostomyy, 57% of them recovered from jaundice, while the remaining 37% had to go for a liver transplant. The 4-year survival rate improved to 89%, indicating that surgical outcomes can be enhanced by centralizing care to supra-regional centers. She evaluated the success ratio of kasai portoenterostomy and demonstrated a higher success and overall survival rate within children who were treated at high volume centers compared to those who were treated at low volume centers. She also identified the need for prompt transfer of care from pediatric to adult-oriented liver treatment centers for patients who have successfully achieved adulthood. She evaluated the prospects of conventional visual screening and systematic screening of babies with neonatal jaundice and suggested that conventional visual screening is not as effective, due to its ability to yield numerous false positives. She identified the need for prompt and incusive transfer of care