sharing hateful sentiments about the opposing side. 49ers tight end Vernon Davis and Cardinals defensive tackle Darnell Dockett were also noted exchanging barbs on Twitter. The results between the two teams were lopsided during this period, with the Cardinals winning one of ten matchups from 2009 to 2013. Then-Cardinals head coach Bruce Arians likened the rivalry to the Browns–Steelers rivalry. However, shifting into the mid-2010s, the Cardinals dominated the 49ers, winning eight straight games in the rivalry from 2015 to 2018. The two teams once again met in Mexico for another Monday Night Football matchup in 2022. 49ers quarterback Jimmy Garoppolo passed for 4 touchdowns in the game, leading his team to a 38–10 victory. Results |- | | style="| Cardinals 27–21 | Kezar Stadium (San Francisco) | Cardinals 1–0 | Cardinals located in Chicago from 1922–1943 and 1945–1959. |- | | style="| Cardinals 20–10 | Kezar Stadium (San Francisco) | Cardinals 2–0 | |- |- | | style="| 49ers 24–17 | Busch Stadium (St. Louis) | Cardinals 2–1 | Cardinals relocated from Chicago to St. Louis in 1960. Teams never faced each other in Chicago. |- | | style="| Cardinals 23–13 | Kezar Stadium (San Francisco) | Cardinals 3–1 | |- | | style="| 49ers 35–17 | Kezar Stadium (San Francisco) | Cardinals 3–2 | |- |- | | style="| 49ers 26–14 | Busch Memorial Stadium (St. Louis) | Tied 3–3 | |- | | style="| Cardinals 34–9 | Candlestick Park (San Francisco) | Cardinals 4–3 | |- | | style="| Cardinals 23–20 (OT) | Busch Memorial Stadium (St. Louis) | Cardinals 5–3 | |- | | style="| Cardinals 16–10 | Candlestick Park (San Francisco) | Cardinals 6–3 | |- | | style="| Cardinals 13–10 | Busch Memorial Stadium (St. Louis) | Cardinals 7–3 | |- |- | | style="| 49ers 24–21 (OT) | Candlestick Park (San Francisco) | Cardinals 7–4 | |- | | style="| 49ers 31–20 | Busch Memorial Stadium (St. Louis) | Cardinals 7–5 | |- | | style="| 49ers 42–27 | Busch Memorial Stadium (St. Louis) | Cardinals 7–6 | |- | | style="| 49ers 43–17 | Candlestick Park (San Francisco) | Tied 7–7 | |- | | style="| 49ers 34–28 | Candlestick Park (San Francisco) | 49ers 8–7 | |- | | style="| Cardinals 24–23 | Sun Devil Stadium (Tempe) | Tied 8–8 | Cardinals relocated to Phoenix, Arizona. Cardinals overcome 23–0 deficit. 49ers