IRAS, combined with its large aperture, favorable fields of view, and long life. Science returns have been accordingly outstanding. Infrared observations are necessary for very distant astronomical objects where all the visible light is redshifted to infrared wavelengths, for cool objects which emit little visible light, and for regions optically obscured by dust. Impact All four telescopes have had a substantial impact on astronomy. The opening up of new wavebands to high resolution, high sensitivity observations by the Compton, Chandra and Spitzer has revolutionized our understanding of a wide range of astronomical objects, and has led to the detection of thousands of new, interesting objects. Hubble has had a much larger public and media impact than the other telescopes, although at optical wavelengths Hubble has provided a more modest improvement in sensitivity and resolution over existing instruments. Hubble's capability for uniform high-quality imaging of any astronomical object at any time has allowed accurate surveys and comparisons of large numbers of astronomical objects. The Hubble Deep Field observations have been very important for studies of distant galaxies, as they provide rest-frame ultraviolet images of these objects with a similar number of pixels across the galaxies as previous ultraviolet images of closer galaxies, allowing direct comparison. The James Webb Space Telescope will provide an even greater step forward, providing rest-frame visible light images of even more distant galaxies which can be directly compared with images of nearby galaxies at visible light wavelengths. Synergies Aside from inherent mission capabilities (particularly sensitivities, which cannot be replicated by ground observatories), the Great Observatories program allows missions to interact for greater science return. Different objects shine in different wavelengths, but training two or more observatories on an object allows a deeper understanding. High-energy studies (in X-rays and gamma rays) have had only moderate imaging resolutions so far. Studying X-ray and gamma-ray objects with Hubble, as well as Chandra and Compton, gives accurate size and positional data. In particular, Hubble's resolution can often discern whether the target is a standalone object, or part of a parent galaxy, and if a bright object is in the nucleus, arms, or halo of a spiral galaxy. Similarly, the smaller aperture of Spitzer means that Hubble can add finer spatial information to a Spitzer image. Ultraviolet studies with Hubble also reveal the temporal states of high-energy objects. X-rays and gamma rays are harder to detect with current technologies than visible and