Quarter Horse although it can occur in other breeds. Research Azumolene is a 30-fold more water-soluble analog of dantrolene that also works to decrease the release of intracellular calcium by its action on the ryanodine receptor. In MH-susceptible swine, azumolene was as potent as dantrolene. It has yet to be studied in vivo in humans, but may present a suitable alternative to dantrolene in the treatment of MH. References External links GeneReview/NIH/UW entry on Malignant Hyperthermia Susceptibility Anesthesia Channelopathies Rare diseases Complications of surgical and medical care Wikipedia medicine articles ready to translate Wikipedia emergency medicine articles ready to translate