This is a list of 599 additives that could be added to tobacco cigarettes. The ABC News program Day One first released the list to the public on March 7, 1994. It was submitted to the United States Department of Health and Human Services in April 1994. They are also listed in the documents that are part of the 1998 Tobacco Master Settlement Agreement. It applies, as documented, only to American manufactured cigarettes intended for distribution within the United States by the listed companies. The five major tobacco companies that reported the information were: American Tobacco Company Brown and Williamson Liggett Group, Inc. Philip Morris Inc. R.J. Reynolds Tobacco Company One significant issue is that while all these chemical compounds have been approved as additives to food, they were not tested by burning. Burning changes the properties of chemicals. Burning creates additional toxic compounds, including carcinogens. According to the U.S. National Cancer Institute: "Of the more than 7,000 chemicals in tobacco smoke, at least 250 are known to be harmful, including hydrogen cyanide, carbon monoxide, and ammonia. Among the 250 known harmful chemicals in tobacco smoke, at least 69 can cause cancer." Although many of these additives are used in making cigarettes, each cigarette does not contain all of these additives. Some of these additives are found in cigarettes outside the USA too. Some American brands are sold in other nations. For example: Marlboro, L&M, Winston, Chesterfield, Kent, and Newport. A Acetanisole Acetic acid Acetoin Acetophenone 6-Acetoxydihydrotheaspirane 2-Acetyl-3-ethylpyrazine 2-Acetyl-5-methylfuran Acetylpyrazine 2-Acetylpyridine 3-Acetylpyridine 2-Acetylthiazole Aconitic acid dl-Alanine Alfalfa extract Allspice extract, oleoresin, and oil Allyl hexanoate Allyl ionone Almond bitter oil Ambergris tincture Ammonia Ammonium bicarbonate Ammonium hydroxide Ammonium sulfide Amyl alcohol Amyl butyrate Amyl formate Amyl octanoate alpha-Amylcinnamaldehyde Amyris oil trans-Anethole Angelica root extract, oil and seed oil Anise Anise star, extract and oils Anisyl acetate Anisyl alcohol Anisyl formate Anisyl phenylacetate Apple juice concentrate, extract, and skins Apricot extract and juice concentrate L-Arginine Asafetida fluid extract and oil Ascorbic acid L-Asparagine monohydrate L-Aspartic acid B Balsam of Peru and oil Basil oil Bay leaf, bay leaf oil, and sweet bay leaf oil Beeswax, white Beet juice concentrate Benzaldehyde Benzaldehyde glyceryl acetal Benzoic acid benzoin Benzoin resin Benzophenone Benzyl alcohol Benzyl benzoate Benzyl butyrate Benzyl cinnamate Benzyl propionate Benzyl salicylate Bergamot oil Bisabolene Black currant buds absolute Borneol Bornyl acetate Buchu leaf oil 1,3-Butanediol 2,3-Butanedione 1-Butanol 2-Butanone 4(2-Butenylidene)-3,5,5-trimethyl-2-cyclohexen-1-one Butter, butter