lungs. Concentrated equine serum reduced EIPH by 53% through a combined mechanism of a 30% reduction in inflammation and an increased functionality of the WBCs. Other anti-inflammatory agents, such as hesperidin-citrus bioflavinoids, vitamin C, NSAIDs such as phenylbutazone, corticosteroids, heated water vapor therapy, cromoglicic acid or nedocromil, have no beneficial effects in reducing EIPH severity. Phenylbutazone can partially reverse the beneficial effects of furosemide. Other ineffective treatments include leukocyte elastase protease inhibitors, the EIPH Patch, hyperbaric oxygen therapy, pentoxyfylline, guanabenz, clonidine, snake venom, and enalapril. Horses that undergo surgical correction for upper airway dysfunction are rested, and are under environmentally controlled environments with reduced dust may see some benefit. References Sources Hinchcliff, K. W. (2009). "Exercise-induced pulmonary hemorrhage". Advances of Equine Nutrition, 4: 367-374. Mason, D. K., E. A. Collins, et al. (1983). Exercise-induced pulmonary haemorrhage in horses. 1st International Conference on Equine Exercise Physiology, Oxford, UK. Roberts, C.A., Hillidge, C. and Marlin, D.J. (1993) Exercise induced pulmonary haemorrhage in racing thoroughbreds in Great Britain. 1st International EIPH Conference, Guelph, Canada, p11. Further reading . Hinchclif, K.W. (2007) Exercise-induced pulmonary haemorrhage in equine respiratory medicine and surgery, eds McGorum, Dixon, Robinson and Schumacher, Saunders Elsevier, page 620-621. Horse diseases