moved in the same direction across the membrane, SGLT1 and SGLT2 are known as symporters. History In August 1960, in Prague, Robert K. Crane presented for the first time his discovery of the sodium-glucose cotransport as the mechanism for intestinal glucose absorption. Crane's discovery of cotransport was the first-ever proposal of flux coupling in biology. See also Cotransport Cotransporter Glucose-galactose malabsorption Renal sodium reabsorption Discovery and development of SGLT-2 inhibitors References External links Solute carrier family