North Main Street Historic District may refer to: North Main Street Historic District (Tuskegee, Alabama), listed on the National Register of Historic Places (NRHP) in Macon County Monticello North Main Street Historic District, Monticello, Arkansas, listed on the NRHP in Drew County North Main Street Historic District (Kennesaw, Georgia), listed on the NRHP in Cobb County North Main Street Commercial Historic District (Statesboro, Georgia), listed on the NRHP in Bulloch County Central Park-North Main Street Historic District, Charles City, Iowa, listed on the NRHP in Floyd County North Main Street Historic District (Greenville, Kentucky), listed on the NRHP in Muhlenberg County North Main Street Historic District (Henderson, Kentucky), listed on the NRHP in Henderson County North Main Street Historic District (Harrodsburg, Kentucky), listed on the NRHP in Mercer County North Main Street Historic District (Madisonville, Kentucky), listed on the NRHP in Hopkins County North Main-North Adams Historic District, Owenton, Kentucky, listed on the NRHP in Owen County North Main Street Historic District (Somerset, Kentucky), listed on the NRHP in Pulaski County North Main Street Historic District (Hattiesburg, Mississippi), listed on the NRHP in Forrest County North Main Street Historic District (Hannibal, Missouri), listed on the NRHP in Marion County North Main Street Historic District (Poplar Bluff, Missouri), listed on the NRHP in Butler County North Main-Bank Streets Historic District, Albion, New York, listed on the NRHP in Orleans County North Main Street Historic District (Canandaigua, New York), listed on the NRHP in Ontario County North Main Street Historic District (East Hampton, New York), listed on the NRHP in Suffolk County North Main Street Historic District (Moravia, New York), listed on the NRHP in Cayuga County North Main Street Historic District (Southampton, New York), listed on the NRHP in Suffolk County North Main Street Historic District (Graham, North Carolina), listed on the NRHP in Alamance County North Main Street Historic District (Mocksville, North Carolina), listed on the NRHP in Davie County North Main Avenue Historic District, Newton, North Carolina, listed on the NRHP in Catawba County North Main Street Historic District (Salisbury, North Carolina), listed on the NRHP in Rowan County North Main-North Detroit Street Historic District, Kenton, Ohio, listed on the NRHP in Hardin County North Main-North Gay Streets Historic District, Mount Vernon, Ohio, listed on the NRHP in Knox County Laverne's North Main Street District, Laverne, Oklahoma, listed on the NRHP in Harper County North Main Street Historic District