evolution of Cit+ in the LTEE was contingent upon mutations that had accumulated earlier. See also Experimental evolution Long-term experiment References Further reading External links E. coli Long-term Experimental Evolution Project Site Bacteria make major evolutionary shift in the lab Bob Holmes New Scientist'' 9 June 2008 Evolution: Past, Present and Future Richard Lenski List of publications on the experiment Online Publication of paper on Rapid evolution of citrate utilization 1988 in biology Biology experiments Escherichia coli Evolutionary biology Molecular evolution