study of ocular tissues and tumors and used histological correlation to refine his technique. Dr. Martel was the first to study the biophysical properties of vitreous using NMR spectroscopy and imaging. After the analysis of this ocular structure, he extended his research into the area of vitreous hemorrhage (bleeding into the eye), an area of great importance in loss of sight. During this time period he explored the use of three dimensional computerized tomography (CT) for the localization and compositional evaluation of intraocular and orbital foreign bodies. He pioneered the technique of deuterium NMR spectroscopy to study metabolism in biological systems. This technique extended the capabilities of existing NMR spectroscopy techniques used to investigate tissue metabolism. Dr. Martel applied his technique to the understanding of diabetic cataract formation and corneal metabolism in order to create new and improved methods of tissue preservation for improved tissue transplantation. He developed a novel method for monitoring activity in multiple metabolic pathways (hexose monophosphate shunt, glycolysis, and the polyol pathway) in the single living lens which allowed insight into the study of diabetic cataractogenesis. and applied to corneal tissue transplantation. His work culminated in the development of chemical shift NMR Microscopy, which combined Magnetic Resonance imaging (MRI) and spectroscopy analysis while working at the Francis Bitter National Magnet Laboratory, Massachusetts Institute of Technology. His research team applied the technique to the study of the living lens to study diabetic cataractogenesis. In 1987, Dr. Aguayo Martel was an invited lecturer at the American Physical Society; the Symposium of the Committee on Applications of Physics: Microtomography-New Three Dimensional Microscopy and presented Grand Rounds at the National Eye Institute, National Institutes of Health on "A New Model of Diabetic Cataractogenesis." The understanding of the metabolism of glucose into sorbitol in the diabetic state has led to the development of a class of medications (aldose reductase inhibitor) to prevent eye and nerve damage in people with diabetes. Dr. Martel is also noted for his work in low illumination ophthalmoscopy and co-inventing the technique of Intraepikeratophakia a precursor to the technique of LASIK. Although Dr. Martel is most noted for his pioneering work in the fields of MRI, NMR spectroscopy, ocular metabolism and diabetes; his most accomplished work has been in the area of acute, ocular emergency and ocular trauma to which he has devoted the past twenty years of his career. Dr. Aguayo Martel continues to serve as