| Washington | W 102–93 | | | | The Spectrum | 46–18 |- align="center" bgcolor="#ccffcc" | 65 | March 19 | Indiana | W 112–95 | | | | The Spectrum | 47–18 |- align="center" bgcolor="#ffcccc" | 66 | March 21 | Boston | L 111–123 | | | | The Spectrum | 47–19 |- align="center" bgcolor="#ffcccc" | 67 | March 24 | New Jersey | L 106–111 | | | | The Spectrum | 47–20 |- align="center" bgcolor="#ffcccc" | 68 | March 25 | @ Detroit | L 98–100 | | | | Pontiac Silverdome | 47–21 |- align="center" bgcolor="#ccffcc" | 70 | March 28 | @ Boston | W 116–98 | | | | Boston Garden | 49–21 |- align="center" bgcolor="#ffcccc" | 71 | March 30 | @ Milwaukee | L 114–116 (OT) | | | | The MECCA | 49–22 |- align="center" bgcolor="#ccffcc" | 76 | April 7 | @ New Jersey | W 116–113 | | | | Brendan Byrne Arena | 53–23 |- align="center" bgcolor="#ffcccc" | 77 | April 9 | @ Atlanta | L 88–103 | | | | The Omni | 54–23 |- align="center" bgcolor="#ffcccc" | 78 | April 11 | Boston | L 109–110 (OT) | | | | The Spectrum | 54–24 |- align="center" bgcolor="#ccffcc" | 79 | April 13 | @ Indiana | W 93–89 | | | | Market Square Arena | 55–24 |- align="center" bgcolor="#ccffcc" | 80 | April 14 | Detroit | W 119–111 | | | | The Spectrum | 56–24 |- align="center" bgcolor="#ccffcc" | 81 | April 16 | @ Washington | W 100–96 | | | | Capital Centre | 57–24 |- align="center" bgcolor="#ccffcc" | 82 | April 18 | Milwaukee | W 110–86 | | | | The Spectrum | 58–24 Playoffs |- align="center" bgcolor="#ccffcc" | 1 | April 21 | Atlanta | W 111–76 | Darryl Dawkins (27) | Darryl Dawkins (9) | Maurice Cheeks (6) | Spectrum11,250 | 1–0 |- align="center" bgcolor="#ccffcc" | 2 | April 23 | @ Atlanta | W 98–95 (OT) | Julius Erving (28) | Dawkins, C. Jones (8) | Julius Erving (6) | Omni Coliseum8,703 | 2–0 |- |- align="center" bgcolor="#ccffcc" | 1 | April 25 | Milwaukee | W 125–122 | Julius Erving (34) | Caldwell Jones (16) | Maurice Cheeks (10) | Spectrum10,086 | 1–0 |- align="center" bgcolor="#ccffcc" | 2 | April 28