Hepatitis B virus X-interacting protein is a protein that in humans is encoded by the HBXIP gene. This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. Interactions HBXIP has been shown to interact with NCOA6. References Further reading Hepatitis B virus