Neutral amino acid transporter A is a protein that in humans is encoded by the SLC1A4 gene. Function The transporter is responsible for transport of L-serine, L-alanine, L-cysteine, and L-threonine. Pathology Mutations of the gene cause a disease called spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM). This disorder is inherited in an autosomal recessive fashion. Interactions In melanocytic cells SLC1A4 gene expression may be regulated by MITF. See also Glutamate transporter Solute carrier family References Further reading Solute carrier family