and is readily brain penetrant. Improves cognitive behavior in animal models In clinical development for cognitive deficits in schizophrenia. A-867744 Ivermectin Other Nefiracetam Antagonists It is found that anandamide and ethanol cause an additive inhibition on the function of α7-receptor by interacting with distinct regions of the receptor. Although ethanol inhibition of the α7-receptor is likely to involve the N-terminal region of the receptor, the site of action for anandamide is located in the transmembrane and carboxyl-terminal domains of the receptors. Anandamide α-Bungarotoxin α-Conotoxin ArIB[V11L,V16D]: potent and highly subtype-selective; slowly reversible β-Caryophyllene Bupropion (very weakly) Dehydronorketamine Ethanol Hydroxybupropion (very weakly) Hydroxynorketamine Ketamine Kynurenic acid Memantine Lobeline Methyllycaconitine Norketamine Quinolizidine (–)-1-epi-207I: α7 subtype preferring blocker See also α3β2-Nicotinic receptor α3β4-Nicotinic receptor α4β2-Nicotinic receptor RIC3, a chaperone protein for α7 receptors Endocannabinoids References Nicotinic acetylcholine receptors Ion channels