New Jersey Devils || 1–1–0–0 || 2 || |- align="center" bgcolor="#ffbbbb" | 3 || October 14 || Phoenix Coyotes || 4–2 || Columbus Blue Jackets || 1–2–0–0 || 2 || |- align="center" bgcolor="#ffbbbb" | 4 || October 17 || Columbus Blue Jackets || 1–7 || St. Louis Blues || 1–3–0–0 || 2 || |- align="center" bgcolor="#bbffbb" | 5 || October 19 || Florida Panthers || 1–4 || Columbus Blue Jackets || 2–3–0–0 || 4 || |- align="center" | 6 || October 23 || Tampa Bay Lightning || 2–2 || Columbus Blue Jackets || 2–3–1–0 || 5 || |- align="center" bgcolor="#ffbbbb" | 7 || October 25 || San Jose Sharks || 5–4 || Columbus Blue Jackets || 2–4–1–0 || 5 || |- align="center" bgcolor="#bbffbb" | 8 || October 27 || Los Angeles Kings || 1–5 || Columbus Blue Jackets || 3–4–1–0 || 7 || |- align="center" bgcolor="#ffbbbb" | 9 || October 29 || Columbus Blue Jackets || 2–3 || Chicago Blackhawks || 3–5–1–0 || 7 || |- |- align="center" bgcolor="#bbffbb" |10 || November 1 || Dallas Stars || 2–4 || Columbus Blue Jackets || 4–5–1–0 || 9 || |- align="center" bgcolor="#bbffbb" |11 || November 3 || Buffalo Sabres || 2–3 || Columbus Blue Jackets || 5–5–1–0 || 11 || |- align="center" bgcolor="#ffffbb" |12 || November 5 || Washington Capitals || 4–3 || Columbus Blue Jackets || 5–5–1–1 || 12 || |- align="center" bgcolor="#bbffbb" |13 || November 7 || Columbus Blue Jackets || 5–2 || St. Louis Blues || 6–5–1–1 || 14 || |- align="center" bgcolor="#bbffbb" |14 || November 9 || New York Rangers || 3–6 || Columbus Blue Jackets || 7–5–1–1 || 16 || |- align="center" bgcolor="#ffbbbb" |15 || November 12 || Columbus Blue Jackets || 4–5 || Colorado Avalanche || 7–6–1–1 || 16 || |- align="center" bgcolor="#ffbbbb" |16 || November 14 || Mighty Ducks of Anaheim || 3–2 || Columbus Blue Jackets || 7–7–1–1 || 16 || |- align="center" |17 || November 16 || Columbus Blue Jackets || 1–1 || Nashville Predators || 7–7–2–1 || 17 || |- align="center" bgcolor="#ffffbb" |18 || November 17 || Columbus Blue Jackets || 2–3 || Dallas Stars || 7–7–2–2 || 18 || |- align="center" bgcolor="#bbffbb" |19 || November 20 || St. Louis Blues || 2–3 || Columbus Blue Jackets || 8–7–2–2 || 20 || |- align="center" bgcolor="#ffbbbb" |20 || November 22 || Columbus Blue Jackets || 4–5 || Buffalo Sabres || 8–8–2–2 || 20