FHEIG (facial dysmorphism, hypertrichosis, epilepsy, developmental/ID delay, and gingival overgrowth) syndrome, manifest accordingly as a constellation of neurological symptoms resulting from neuronal dysplasia. Animal models containing known syndromic KCNK4 mutations have recapitulated these phenotypic abnormalities. High TRAAK channel density has also been implicated in the resulting cerebral ischemia following the event of a stroke. See also Tandem pore domain potassium channel References Further reading External links Ion channels