This article deals with activities of the U.S. Central Intelligence Agency related to transnational crime, including the illicit drug trade. Two offices of the CIA Directorate of Intelligence have analytical responsibilities in this area. The Office of Transnational Issues applies unique functional expertise to assess existing and emerging threats to US national security and provides the most senior US policymakers, military planners, and law enforcement with analysis, warning, and crisis support. The CIA Crime and Narcotics Center researches information on international narcotics trafficking and organized crime for policymakers and the law enforcement community. Since the CIA has no domestic police authority, it sends its analytic information to the Federal Bureau of Investigation (FBI) and other law enforcement organizations, such as the Drug Enforcement Administration (DEA) and the Office of Foreign Assets Control of the United States Department of the Treasury (OFAC). Another part of the CIA, the National Clandestine Service, collects human intelligence (HUMINT) in these areas. Drug trade According to the United Nations Office on Drugs and Crime (UNODOC), Drug cultivation thrives on instability, corruption and poor governance. The world's biggest drug producing centres are in regions beyond the control of the central government, like South Afghanistan, South-West Colombia and East Myanmar. Until government control, democracy and the rule of law are restored, these regions will remain nests of insurgency and drug production—and represent the biggest challenge to containment. Especially in developing countries in conflict, there have been allegations that the CIA assisted the illicit drug activities of local leaders who saw that as a payment for their assistance. Counternarcotics mission CIA publishes reference materials in this area, such as "Heroin Movement Worldwide". CIA supported a reevaluation of US antidrug priorities by the President's Office of National Drug Control Policy by publishing a paper that addressed the strategic vulnerabilities of the global drug trade. The paper addressed the exploitable operational, logistical, financial, and geographic weakness of the many criminal enterprises that supply narcotics to the United States and other markets. The paper was well received by the Director of the Office of National Drug Control Policy, and he instructed the law enforcement community to use it as a template to craft a companion product addressing the vulnerabilities of the US domestic drug trade. CIA analysts wrote the first-ever analysis of drug flows and consumption in Brazil, the world's second-largest consumer of cocaine after the United States. The study entailed