|| Wickman (16) || 40,792 || 34–35 |-align="center" bgcolor="ffbbbb" | 70 || June 18 || @ Marlins || 4–0 || Dempster (5–6) || Finley (4–8) || || 9,724 || 34–36 |-align="center" bgcolor="ffbbbb" | 71 || June 19 || @ Marlins || 2–1 || Tavárez (5–3) || Riggan (1–1) || Núñez (16) || 9,428 || 34–37 |-align="center" bgcolor="ffbbbb" | 72 || June 20 || @ Marlins || 3–0 (6) || Burnett (8–5) || Drese (7–5) || || 8,045 || 34–38 |-align="center" bgcolor="ffbbbb" | 73 || June 21 || @ Expos || 3–1 || Vázquez (5–3) || Sabathia (5–6) || Stewart (8) || 7,494 || 34–39 |-align="center" bgcolor="bbffbb" | 74 || June 22 || @ Expos || 5–4 || Colón (10–4) || Day (2–1) || Wickman (17) || 10,180 || 35–39 |-align="center" bgcolor="ffbbbb" | 75 || June 23 || @ Expos || 7–2 || Armas Jr. (7–7) || Finley (4–9) || || 13,557 || 35–40 |-align="center" bgcolor="bbffbb" | 76 || June 25 || @ Red Sox || 4–2 || Báez (6–5) || Castillo (5–8) || Wickman (18) || 34,064 || 36–40 |-align="center" bgcolor="ffbbbb" | 77 || June 26 || @ Red Sox || 7–4 || Martínez (9–2) || Drese (7–6) || Urbina (21) || 32,255 || 36–41 |-align="center" bgcolor="bbffbb" | 78 || June 28 || Diamondbacks || 8–2 || Sabathia (6–6) || Batista (4–5) || || 42,586 || 37–41 |-align="center" bgcolor="ffbbbb" | 79 || June 29 || Diamondbacks || 4–2 || Anderson (3–7) || Finley (4–10) || Kim (20) || 42,466 || 37–42 |-align="center" bgcolor="ffbbbb" | 80 || June 30 || Diamondbacks || 5–2 || Schilling (13–3) || Báez (6–6) || || 42,221 || 37–43 |- |-align="center" bgcolor="ffbbbb" | 81 || July 2 || @ Yankees || 10–5 || Mendoza (6–2) || Rincón (0–3) || || 45,589 || 37–44 |-align="center" bgcolor="ffbbbb" | 82 || July 3 || @ Yankees || 11–8 || Wells (9–5) || Sabathia (6–7) || Rivera (20) || 39,879 || 37–45 |-align="center" bgcolor="ffbbbb" | 83 || July 4 || @ Yankees || 7–1 || Mussina (12–3) || Finley (4–11) || || 42,909 || 37–46 |-align="center" bgcolor="bbffbb" | 84 || July 5 || @ White Sox || 4–2 || Báez (7–6) || Garland (7–6) || Wickman (19) || 29,085 || 38–46 |-align="center" bgcolor="ffbbbb" | 85 || July 6 || @ White Sox || 7–3 || Buehrle (12–6) || Phillips (0–1) || Marte (1) || 25,016 || 38–47 |-align="center" bgcolor="bbffbb" |