In enzymology, a pantothenase () is an enzyme that catalyzes the chemical reaction (R)-pantothenate + H2O (R)-pantoate + beta-alanine Thus, the two substrates of this enzyme are (R)-pantothenate and H2O, whereas its two products are (R)-pantoate and beta-alanine. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is (R)-pantothenate amidohydrolase. Other names in common use include pantothenate hydrolase, and pantothenate amidohydrolase. This enzyme participates in pantothenate and coa biosynthesis. References EC 3.5.1 Enzymes of unknown structure