In enzymology, a D-glutaminase () is an enzyme that catalyzes the chemical reaction D-glutamine + H2O D-glutamate + NH3 Thus, the two substrates of this enzyme are D-glutamine and H2O, whereas its two products are D-glutamate and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is D-glutamine amidohydrolase. This enzyme participates in d-glutamine and d-glutamate metabolism and nitrogen metabolism. References EC 3.5.1 Enzymes of unknown structure