In enzymology, a thiocyanate hydrolase () is an enzyme that catalyzes the chemical reaction thiocyanate + 2 H2O carbonyl sulfide + NH3 + HO- Thus, the two substrates of this enzyme are thiocyanate and H2O, whereas its 3 products are carbonyl sulfide, NH3, and HO-. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is thiocyanate aminohydrolase. Structural studies As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and . References EC 3.5.5 Enzymes of known structure