In enzymology, a N-malonylurea hydrolase () is an enzyme that catalyzes the chemical reaction 3-oxo-3-ureidopropanoate + H2O malonate + urea Thus, the two substrates of this enzyme are 3-oxo-3-ureidopropanoate and H2O, whereas its two products are malonate and urea. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming). This enzyme is also called ureidomalonase. References EC 3.5.1 Enzymes of unknown structure