|| Miller (1) || 25,737 || 24-25 |-align="center" bgcolor="#bbffbb" | 50 || May 31 || @ Twins || 4 – 3 || Sabathia (4-3) || Silva (3-3) || Wickman (14) || 15,494 || 25-25 |- |-align="center" bgcolor="#ffbbbb" | 51 || June 1 || @ Twins || 6 – 2 || Radke (5-4) || Lee (6-3) || || 20,739 || 25-26 |-align="center" bgcolor="#ffbbbb" | 52 || June 2 || @ Twins || 4 – 3 (13) || Romero (1-2) || Betancourt (1-2) || || 17,351 || 25-27 |-align="center" bgcolor="#ffbbbb" | 53 || June 3 || @ White Sox || 6 – 4 || Hernández (6-1) || Westbrook (2-8) || Hermanson (12) || 23,132 || 25-28 |-align="center" bgcolor="#ffbbbb" | 54 || June 4 || @ White Sox || 6 – 5 || Garland (9-2) || Davis (2-2) || Hermanson (13) || 26,365 || 25-29 |-align="center" bgcolor="#bbffbb" | 55 || June 5 || @ White Sox || 6 – 4 (12) || Riske (2-2) || Hermanson (0-1) || || 26,146 || 26-29 |-align="center" bgcolor="#bbffbb" | 56 || June 7 || @ Padres || 2 – 0 (11) || Betancourt (2-2) || Hoffman (0-2) || Wickman (15) || 25,047 || 27-29 |-align="center" bgcolor="#bbffbb" | 57 || June 8 || @ Padres || 6 – 1 || Elarton (3-2) || Peavy (5-1) || Howry (2) || 29,464 || 28-29 |-align="center" bgcolor="#ffbbbb" | 58 || June 9 || @ Padres || 3 – 2 || Eaton (9-1) || Westbrook (2-9) || Hoffman (17) || 27,149 || 28-30 |-align="center" bgcolor="#bbffbb" | 59 || June 10 || @ Giants || 10 – 2 || Sabathia (5-3) || Tomko (5-8) || || 37,102 || 29-30 |-align="center" bgcolor="#bbffbb" | 60 || June 11 || @ Giants || 7 – 6 || Davis (3-2) || Schmidt (3-3) || Wickman (16) || 39,961 || 30-30 |-align="center" bgcolor="#bbffbb" | 61 || June 12 || @ Giants || 5 – 3 || Lee (7-3) || Rueter (2-5) || Wickman (17) || 41,500 || 31-30 |-align="center" bgcolor="#bbffbb" | 62 || June 14 || Rockies || 11 – 2 || Westbrook (3-9) || Francis (5-4) || || 17,631 || 32-30 |-align="center" bgcolor="#bbffbb" | 63 || June 15 || Rockies || 7 – 6 (11) || Howry (4-1) || Neal (1-2) || || 20,986 || 33-30 |-align="center" bgcolor="#bbffbb" | 64 || June 16 || Rockies || 2 – 1 || Millwood (2-4) || Wright (4-6) || Wickman