sweet taste. This suggests that activation of the G-protein pathway and subsequent activation of PLC β2 and the TRPM5 channel in these taste cells functions to activate the cell. Location and innervation TAS1R1+3 expressing cells are found mostly in the fungiform papillae at the tip and edges of the tongue and palate taste receptor cells in the roof of the mouth. These cells are shown to synapse upon the chorda tympani nerves to send their signals to the brain, although some activation of the glossopharyngeal nerve has been found. TAS1R and TAS2R (bitter) channels are not expressed together in taste buds. See also Taste receptor TAS1R2 TAS1R3 References Further reading External links TAS1R1 Gene TASTE RECEPTOR TYPE 1, MEMBER 1; TAS1R1 Human taste receptors