In enzymology, a N-methyl-2-oxoglutaramate hydrolase () is an enzyme that catalyzes the chemical reaction N-methyl-2-oxoglutaramate + H2O 2-oxoglutarate + methylamine Thus, the two substrates of this enzyme are N-methyl-2-oxoglutaramate and H2O, whereas its two products are 2-oxoglutarate and methylamine. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-methyl-2-oxoglutaramate methylamidohydrolase. This enzyme is also called 5-hydroxy-N-methylpyroglutamate synthase. References EC 3.5.1 Enzymes of unknown structure