In enzymology, a glutamin-(asparagin-)ase () is an enzyme that catalyzes the chemical reaction L-glutamine + H2O L-glutamate + NH3 Thus, the two substrates of this enzyme are L-glutamine and H2O, whereas its two products are L-glutamate and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is L-glutamine(L-asparagine) amidohydrolase. This enzyme participates in 4 metabolic pathways: glutamate metabolism, alanine and aspartate metabolism, d-glutamine and d-glutamate metabolism, and nitrogen metabolism. Structural studies As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and . References EC 3.5.1 Enzymes of known structure