Empalme (Spanish: "junction", "splice", "union") may refer to Places Empalme, Sonora, city in northern Mexico Empalme Villa Constitución, town in the Argentine province of Santa Fe El Empalme, town in the Ecuadorian province of Guayas Empalme Escobedo, in the Mexican state of Guanajuato Empalme Nicolich, in Uruguay Empalme Olmos, in Uruguay Other Empalme (food), tortilla sandwich originating in the Mexican state of Nuevo León Empalme (Madrid Metro), station on Line 5 of the Madrid Metro