3 – 2 || Boyd (3-1) || Shields (2-3) || Báez (25) || 20,116 || 49-68 |-align="center" bgcolor="#bbffbb" | 118 || August 10 || Angels || 3 – 1 || Sabathia (10-7) || Lackey (7-11) || Betancourt (1) || 23,576 || 50-68 |-align="center" bgcolor="#ffbbbb" | 119 || August 11 || @ Twins || 5 – 3 || Lohse (9-9) || Westbrook (5-7) || Hawkins (1) || 23,291 || 50-69 |-align="center" bgcolor="#bbffbb" | 120 || August 12 || @ Twins || 9 – 6 || Betancourt (2-1) || Baldwin (0-1) || || 25,834 || 51-69 |-align="center" bgcolor="#bbffbb" | 121 || August 13 || @ Twins || 5 – 0 (14) || Mulholland (2-2) || Rincón (3-5) || || 30,082 || 52-69 |-align="center" bgcolor="#bbffbb" | 122 || August 14 || @ Twins || 8 – 3 || Anderson (9-9) || Radke (8-10) || || 24,273 || 53-69 |-align="center" bgcolor="#bbffbb" | 123 || August 15 || Devil Rays || 1 – 0 || Sabathia (11-7) || Harper (2-7) || || 19,679 || 54-69 |-align="center" bgcolor="#ffbbbb" | 124 || August 16 || Devil Rays || 5 – 3 || Malaska (2-1) || Lee (1-1) || Carter (21) || 23,397 || 54-70 |-align="center" bgcolor="#bbffbb" | 125 || August 17 || Devil Rays || 5 – 4 (12) || Mulholland (3-2) || Colomé (3-6) || || 21,097 || 55-70 |-align="center" bgcolor="#ffbbbb" | 126 || August 18 || Devil Rays || 7 – 4 (13) || Carter (7-3) || Mulholland (3-3) || || 18,685 || 55-71 |-align="center" bgcolor="#ffbbbb" | 127 || August 19 || Twins || 8 – 2 || Santana (7-3) || Davis (7-10) || || 21,239 || 55-72 |-align="center" bgcolor="#ffbbbb" | 128 || August 20 || Twins || 4 – 3 || Radke (9-10) || Anderson (9-10) || Guardado (28) || 20,197 || 55-73 |-align="center" bgcolor="#bbffbb" | 129 || August 22 || @ Devil Rays || 8 – 3 || Lee (2-1) || Kennedy (3-10) || || 11,979 || 56-73 |-align="center" bgcolor="#bbffbb" | 130 || August 23 || @ Devil Rays || 7 – 5 || Sabathia (12-7) || Backe (1-1) || Riske (2) || 18,805 || 57-73 |-align="center" bgcolor="#bbffbb" | 131 || August 24 || @ Devil Rays || 7 – 5 || Westbrook (6-7) || González (6-6) || Riske (3) || 14,507 || 58-73 |-align="center" bgcolor="#ffbbbb" | 132 || August 26 || Tigers || 5 – 4 || Cornejo (6-13) || Traber (6-7)