diverse molecules in a cell by using an antibody and its reaction with a specific antigen (in this case, it was used an antibody called anti-ATAT1 antibody). In this study, ATAT1 was observed in many tissues and scientifics discovered and were able to suppose some of its functions. This last study allowed to reveal the intracellular distribution of ATAT1 in ciliated cells of some tissues. Location ATAT1 is known to be located in: Trachea It is manly located at the apical region of epithelial cells, but its function is still an enigma. Kidney The immunopositive signal caused by the anti-ATAT1 antibody was observed in epithelial cells of the medullary collecting duct. Retina The α-tubulin N-acetyltransferase is mainly located in photoreceptor cells. Moreover, ATAT1 is thought to be associated not only with the connecting cilia and the axonemes of the outer segment (OS), but also with the entire inner segment (IS) and the entire outer segment (OS). Therefore, it might play an important paper in the intracilial transport of signal proteins during light-sensing signaling in photoreceptor cells. Testis In testis, the antibody was observed in spermatocytes and spermatids, but not in sperm. In spermatocytes, it was also seen that ATAT1 was located around the Golgi apparatus, which indicates that this protein might play an important paper in spermatogenesis. Third ventricle Although it is still unclear the function o ATAT1, it was also found in other tissues such as the third ventricle of the brain, but its specific function is unknown. However, it is considered to play an important role in neurone development. Subcellular location Alpha-tubulin N-acetyltransferase is located in several parts of the cell such as in the cytoskeleton, cytoplasm, or the clathrin coated-pit in the membrane. This is closely related to one of its main functions which is the catalysis of microtubule acetylation. Mutagenesis and mutations ATAT1 might tend to undergo a process known as mutagenesis according to which, a genetic mutation is produced. This may occur spontaneously or, on the other hand, due to the action of mutagens. It is possible to classify the different results of mutagenesis depending on which of the 421 aminoacids have been changed. If glutamine (Q), which occupies the 58th position in the sequence of aminoacids is substituted by alanine (A) a loss in the acetyltransferase activity will be produced. The consequence of a mutation in which the isoleucine (I) in 64th place is