In enzymology, a (S)-N-acetyl-1-phenylethylamine hydrolase () is an enzyme that catalyzes the chemical reaction N-acetylphenylethylamine + HO phenethylamine + acetate Thus, the two substrates of this enzyme are N-acetylphenylethylamine and HO, whereas its two products are phenethylamine and acetate. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is (S)-N-acetylphenylethylamine:HO hydrolase. At least one compound, phenylmethanesulfonylfluoride is known to inhibit this enzyme. References EC 3.5.1 Enzymes of unknown structure