In 2002, in the movie Avassaladoras, she played Laura, a successful woman who seeks a boyfriend through a wedding agency. In the film, she stars with Reynaldo Gianecchini, with whom she would appear in other works on TV. Participation in the film earned Antonelli the Crystal Lens Award for Best Actress at the Brazilian Film Festival in Miami. After multiple successes, Antonelli's career was divided between soap operas, miniseries and films. Avassaladoras (2002) was her first film playing a protagonist. In 2003, Giovanna starred in the miniseries A Casa das Sete Mulheres, by Maria Adelaide Amaral and Walter Negrão, playing Anita Garibaldi. At that time, she received several accolades for her resourcefulness, originality and the way in which she disengaged herself from the brand of her previous character Jade who had launched her to stardom in Brazil. She played the Virgin Mary in the film Maria, Mãe do Filho de Deus,(2003) directed by Moacyr Góes and in the theater appeared in A Paixão de Cristo. Her performance in the film was praised by some critics but criticized by others who thought that her performance lacked brilliance. In 2004, she portrayed her first villain, Barbara, in the telenovela Da Cor do Pecado (2004), by João Emanuel Carneiro. She received critical acclaim for acting in a way that erased viewers' memories of the characters with a reputation for being a good girl who had played previously. In the theater she appeared with actor Murilo Benício in Dois na Gangorra, directed by Walter Lima Júnior, and in film in the movie A Cartomante, directed by Wagner de Assis and Pablo Uranga. The film itself was widely criticized and is considered one of the worst films of 2004. 2007–2010: Sete Pecados, Três Irmãs and Viver a Vida In 2007, Antonelli returned to TV as Delzuite, the protagonist of the first part of the miniseries, Amazônia, de Galvez a Chico Mendes, by Glória Perez. In the same year, he was the protagonist in the telenovela Sete Pecados (2007) by Walcyr Carrasco, where her character Clarice lives a love triangle with Dante (Reynaldo Gianecchini) and Beatriz Priscila Fantin). She also appeared in the long film Caixa Dois, directed by Bruno Barreto, in the role of a secretary to a powerful banker.. Her performance was criticized and her role considered "the weak point of the plot". In 2008, Giovanna showed her comic side, interpreting the clumsy Alma