Marlins || 7–6 || Beimel (2–0) ||Gregg (3–1) || Saito (3) ||11,334 || 13–13 |- align="center" bgcolor="#bbffbb" | 27 || April 30 || @ Marlins || 13–1 ||Billingsley (1–4) ||Olsen (3–1) || || 10,792|| 14–13 |- |- align="center" bgcolor="#bbffbb" | 28 || May 1 || @ Marlins || 5–3 || Beimel (3–0)|| Gregg (3–2) || Saito (4)|| 15,556||15–13 |- align="center" bgcolor="#bbffbb" | 29 || May 2 || @ Rockies || 11–6 ||Penny (5–2)|| Francis (0–3) || ||30,291 ||16–13 |- align="center" bgcolor="#bbffbb" | 30 || May 3 || @ Rockies || 12–7 ||Kuo (1–1) || de la Rosa (0–1) || || 38,597||17–13 |- align="center" bgcolor="#ffbbbb" | 31 || May 4 || @ Rockies || 7–2 || Cook (5–1) ||Lowe (2–2) || Buchholz (1)||43,726 ||17–14 |- align="center" bgcolor="#bbffbb" | 32 || May 5 || Mets || 5–1 || Billingsley (2–4)|| Pérez (2–3)|| ||44,181 ||18–14 |- align="center" bgcolor="#bbffbb" | 33 || May 6 || Mets || 5–4 ||Kuo (2–1) ||Figueroa (2–2) ||Saito (5) ||43,927 ||19–14 |- align="center" bgcolor="#ffbbbb" | 34 || May 7 || Mets || 12–1 || Maine (4–2) || Penny (5–3) || ||40,696 ||19–15 |- align="center" bgcolor="#ffbbbb" | 35 || May 9 || Astros || 7–1 || Moehler (1–0)||Lowe (2–3) || ||52,658 ||19–16 |- align="center" bgcolor="#ffbbbb" | 36 || May 10 || Astros || 5–0 || Sampson (2–3) ||Billingsley (2–5) || ||45,212 ||19–17 |- align="center" bgcolor="#ffbbbb" | 37 || May 11 || Astros || 8–5 || Geary (1–1) || Broxton (1–1) || Valverde (8) || 40,217 || 19–18 |- align="center" bgcolor="#ffbbbb" | 38 || May 13 || @ Brewers || 5–3 || Villanueva (2–4) ||Penny (5–4) || Gagné (10) ||26,465 ||19–19 |- align="center" bgcolor="#bbffbb" | 39 || May 14 || @ Brewers || 6–4 ||Broxton (2–1) ||Mota (1–2) || Saito (6) ||27,562 ||20–19 |- align="center" bgcolor="#bbffbb" | 40 || May 15 || @ Brewers || 7–2 || Billingsley (3–5) ||Sheets (4–1) || ||30,444 ||21–19 |- align="center" bgcolor="#ffbbbb" | 41 || May 16 || @ Angels || 4–2 || Saunders (7–1) || Kuroda (1–3) || Rodríguez (17)||44,047 || 21–20 |- align="center" bgcolor="#bbffbb" | 42 || May 17 || @ Angels || 6–3 || Kuo (3–1) || Santana (6–1) || ||43,906 ||22–20 |- align="center" bgcolor="#ffbbbb" | 43 || May 18 || @ Angels || 10–2 || Weaver (3–5) || Lowe (2–4) || || 44,007 || 22–21 |- align="center" bgcolor="#bbffbb" | 44 || May 19 || Reds || 6–5 || Saito (2–1) || Weathers