successful plans for increasingly complex problems and Knowledge-based interlingual machine translation. He was instrumental in setting up the Computational Biolinguistics Program, a joint venture between Carnegie Mellon and the University of Pittsburgh, which combines Language Technologies and Machine Learning to model and predict genomic, proteomic and glycomic 3D structures. Carbonell was particularly well known in machine learning. He organized the first four machine learning conferences, starting with CMU in 1981. The Language Technologies Institute (LTI), founded and directed by Carbonell, achieved top honors in multiple areas. These areas include machine translation, search engines (including founding of Lycos by Michael Mauldin, one of Carbonell’s PhD students), speech synthesis, and education. LTI remains the original, largest and best-known institute for language technologies, with over $12M in annual funding and 200 researchers (faculty, staff, PhD students, MS students, visiting scholars etc.). Carbonell made major technical contributions in several fields, including (1) Creation of MMR (maximal marginal relevance) technology for text summarization and informational novelty detection in search engines,(2) Proactive machine learning for multi-source cost-sensitive active learning, (3) Linked conditional random fields for predicting tertiary and quaternary protein folds, (4) Symmetric optimal phrasal alignment method for trainable example-based and statistical machine translation, (5) Series- anomaly modeling for financial fraud detection and syndromic surveillance, (6) Knowledge-based interlingual machine translation, (7) Robust case-frame parsing, (8) Seeded version-space learning and (9) Invention of transformational and derivational analogy, generalized methods for case-based reasoning (CBR) to re-use, modify and compose past successful plans for increasingly complex problems. The teams led by Carbonell achieved top honors in many areas such as first scalable high-accuracy interlingual machine translation (1991), first speech-to-speech machine translation (1992), first large-scale spider and search engine (1994), and first trainable, large-scale protein-structure topology predictor (2005). Modern machine learning, co-founded by Carbonell, Michalski and Mitchell, is a fundamental enabling technology in search engines, data mining and social networking. Starting in 1980, he co-edited the first three books on ML, launched the ML conferences and was a co-founder and editor-in-chief of ML Journal. Carbonell’s innovations have led to several successful start-ups: Carnegie Group (AI expertsystems), Lycos (web search), Wisdom (financial optimization & ML), Carnegie Speech (spoken-language tutoring), Dynamix (data mining and pattern discovery), and Meaningful Machines (context-based machine translation). Carbonell was the founding director of The Language Technology Institute, the preeminent global institution in language studies, unparalleled in size and scope and has since been adopted/imitated in Germany (DFKI),