38,991 || 29–23 || L2 |-style="background:#cfc;" | 53 || June 7 || 2:20p.m. CDT || @ Dodgers || W 7–5 || López (1–0) || Howell (2–3) || Smith (14) || 3:27 || 32,902 || 30–23 || W1 |-style="background:#cfc;" | 54 || June 8 || 3:05p.m. CDT || @ Dodgers || W 3–2 || Scott (6–4) || Valenzuela (8–4) || Smith (15) || 2:44 || 47,404 || 31–23 || W2 |-style="background:#cfc;" | 55 || June 9 || 9:05p.m. CDT || @ Padres || W 5–3 || Deshaies (2–2) || Show (3–4) || López (1) || 2:42 || 19,167 || 32–23 || W3 |-style="background:#cfc;" | 56 || June 10 || 9:05p.m. CDT || @ Padres || W 12–1 || Knepper (10–3) || Dravecky (5–6) || — || 2:31 || 13,966 || 33–23 || W4 |-style="background:#fcc;" | 57 || June 11 || 3:05p.m. CDT || @ Padres || L 7–11 || McCullers (2–1) || DiPino (1–2) || — || 2:47 || 13,686 || 33–24 || L1 |-style="background:#cfc;" | 58 || June 12 || 7:35p.m. CDT || Giants || W 4–1 || Hernández (1–1) || Krukow (8–4) || Smith (16) || 2:37 || 16,342 || 34–24 || W1 |-style="background:#fcc;" | 59 || June 13 || 7:35p.m. CDT || Giants || L 1–3 || Davis (2–3) || Scott (6–5) || — || 2:22 || 23,352 || 34–25 || L1 |-style="background:#cfc;" | 60 || June 14 || 7:35p.m. CDT || Giants || W 7–3 || Deshaies (3–2) || Mulholland (0–1) || López (2) || 2:48 || 32,477 || 35–25 || W1 |-style="background:#fcc;" | 61 || June 15 || 2:05p.m. CDT || Giants || L 2–7 || Blue (4–3) || Knepper (10–4) || — || 2:56 || 22,958 || 35–26 || L1 |-style="background:#fcc;" | 62 || June 17 || 6:35p.m. CDT || @ Reds || L 4–5 || Welsh (2–1) || Hernández (1–2) || Franco (11) || 2:33 || 16,824 || 35–27 || L2 |-style="background:#fcc;" | 63 || June 18 || 6:35p.m. CDT || @ Reds || L 2–3 || Robinson (5–0) || Smith (1–3) || — || 2:20 || 17,426 || 35–28 || L3 |-style="background:#cfc;" | 64 || June 19 || 6:35p.m. CDT || @ Reds || W 6–2 || Deshaies (4–2) || Soto (3–7) || — || 2:54 || 25,920 || 36–28 || W1 |-style="background:#fcc;" | 65 || June 20 || 10:05p.m. CDT || @ Giants || 1–3 || Blue (5–3) || Knepper (10–5) ||