— || 2:46 || 30,598 || 73–56 || L1 |-style="background:#fcc;" | 130 || August 31 || 2:05p.m. CDT || Pirates || L 2–8 || Walk (7–7) || Knepper (15–10) || — || 2:17 || 25,405 || 73–57 || L2 |- |-style="background:#cfc;" | 131 || September 1 || 1:20p.m. CDT || @ Cubs || W 6–4 || Darwin (7–9) || Lynch (4–4) || Smith (28) || 3:01 || 25,547 || 74–57 || W1 |-style="background:#cfc;" | 132 || September 2 || 3:05p.m. CDT || @ Cubs || W 8–7 || Darwin (8–9) || Maddux (0–1) || — || 5:14 || 10,501 || 75–57 || W2 |-style="background:#cfc;" | 133 || September 3 || 1:20p.m. CDT || @ Cubs || W 8–2 || Scott (15–9) || Sanderson (7–11) || — || 2:48 || 7,051 || 76–57 || W3 |-style="background:#fcc;" | 134 || September 5 || 7:35p.m. CDT || Cardinals || L 5–8 || Soff (2–0) || López (3–2) || — || 2:50 || 23,547 || 76–58 || L1 |-style="background:#cfc;" | 135 || September 6 || 7:35p.m. CDT || Cardinals || W 7–6 || Kerfeld (9–2) || Worrell (8–10) || — || 2:58 || 21,802 || 77–58 || W1 |-style="background:#cfc;" | 136 || September 7 || 2:05p.m. CDT || Cardinals || W 6–3 || Calhoun (1–0) || Mathews (10–5) || Smith (29) || 2:50 || 20,773 || 78–58 || W2 |-style="background:#cfc;" | 137 || September 8 || 7:35p.m. CDT || Reds || W 3–1 || Ryan (10–8) || Welsh (5–6) || Kerfeld (7) || 2:26 || 26,997 || 79–58 || W3 |-style="background:#cfc;" | 138 || September 9 || 7:35p.m. CDT || Reds || W 9–2 || Scott (16–9) || Browning (12–12) || — || 2:11 || 22,711 || 80–58 || W4 |-style="background:#fcc;" | 139 || September 10 || 9:35p.m. CDT || @ Dodgers || L 1–5 || Hershiser (13–10) || Deshaies (9–5) || — || 2:56 || 27,534 || 80–59 || L1 |-style="background:#fcc;" | 140 || September 11 || 9:35p.m. CDT || @ Dodgers || L 6–14 || Valenzuela (19–9) || Knepper (15–11) || — || 2:51 || 34,816 || 80–60 || L2 |-style="background:#cfc;" | 141 || September 12 || 9:05p.m. CDT || @ Padres || W 5–3 || Kerfeld (10–2) || McCullers (8–8) || Smith (30) || 2:35 || 11,319 || 81–60 || W1 |-style="background:#fcc;" | 142 || September 13 || 9:05p.m. CDT || @ Padres || L 3–4 || Lefferts (8–7) || Smith