background:#bfb;" | 135 || August 31 || Orioles || 10–4 || Shields (12–8) || Burres (7–9) || || 32,379 || 84–51 |- |- style="text-align:center; background:#fbb;" | 136 || September 2 || Yankees || 7–2 || Mussina (17–7) || Garza (11–8) || || 21,629 || 84–52 |- style="text-align:center; background:#fbb;" | 137 || September 3 || Yankees || 8–4 || Ramírez (5–1) || Jackson (11–9) || || 25,215 || 84–53 |- style="text-align:center; background:#bfb;" | 138 || September 4 || Yankees || 7–5 || Kazmir (11–6) || Rasner (5–10) || Wheeler (11) || 26,080 || 85–53 |- style="text-align:center; background:#fbb;" | 139 || September 5 || @ Blue Jays || 6–4 || Halladay (18–9) || Sonnanstine (13–7) || Ryan (27) || 32,477 || 85–54 |- style="text-align:center; background:#fbb;" | 140 || September 6 || @ Blue Jays || 7–4 (13) || Tallet (1–1) || Percival (2–1) || || 34,469 || 85–55 |- style="text-align:center; background:#fbb;" | 141 || September 7 || @ Blue Jays || 1–0 || Purcey (3–5) || Garza (11–9) || Carlson (2) || 39,854 || 85–56 |- style="text-align:center; background:#fbb;" | 142 || September 8 || @ Red Sox || 3–0 || Lester (14–5) || Jackson (11–10) || Papelbon (36) || 37,662 || 85–57 |- style="text-align:center; background:#bfb;" | 143 || September 9 || @ Red Sox || 5–4 || Wheeler (4–5) || Papelbon (5–4) || Percival (28) || 37,573 || 86–57 |- style="text-align:center; background:#bfb;" | 144 || September 10 || @ Red Sox || 4–2 || Miller (2–0) || Timlin (4–4) || Hammel (1) || 38,114 || 87–57 |- style="text-align:center; background:#bbb;" | || September 12 || @ Yankees || colspan=6|Postponed (rain) Rescheduled for September 13 |- style="text-align:center; background:#bfb;" | 145 || September 13 || @ Yankees || 7–1 || Shields (13–8) || Mussina (17–9) || || 54,088 || 88–57 |- style="text-align:center; background:#fbb;" | 146 || September 13 || @ Yankees || 6–5 || Marte (5–3) || Howell (6–1) || Rivera (34) || 53,568 || 88–58 |- style="text-align:center; background:#fbb;" | 147 || September 14 || @ Yankees || 8–4 || Pavano (3–1) || Jackson (11–11) || Rivera (35) || 54,279 || 88–59 |- style="text-align:center; background:#fbb;" | 148 || September 15 || Red Sox || 13–5 || Matsuzaka (17–2) || Kazmir (11–7) || || 29,772 || 88–60 |- style="text-align:center; background:#bfb;" | 149 || September 16 || Red Sox || 2–1 || Wheeler (5–5) || Masterson (6–5) || || 32,079 || 89–60 |- style="text-align:center; background:#bfb;" | 150