14 || April 23 || 4:40p.m. CST || @ Braves || W 3–2 || Solano (1–0) || Smith (1–1) || Smith (6) || 2:27 || 7,666 || 10–4 || W2 |-style="background:#fcc;" | 15 || April 24 || 7:35p.m. CST || Reds || L 0–3 || Soto (2–1) || Madden (1–1) || — || 2:35 || 10,245 || 10–5 || L1 |-style="background:#cfc;" | 16 || April 25 || 7:35p.m. CST || Reds || W 3–1 || Ryan (3–2) || Browning (0–2) || — || 2:07 || 16,296 || 11–5 || W1 |-style="background:#cfc;" | 17 || April 26 || 7:35p.m. CST || Reds || W 1–0 || Scott (2–2) || Gullickson (0–2) || — || 2:06 || 38,442 || 12–5 || W2 |-style="background:#cfc;" | 18 || April 27 || 2:05p.m. CDT || Reds || W 6–0 || Knepper (4–0) || Denny (1–2) || — || 2:06 || 12,185 || 13–5 || W3 |-style="background:#fcc;" | 19 || April 29 || 6:35p.m. CDT || @ Phillies || L 4–12 || Rawley (3–1) || Ryan (3–3) || — || 2:48 || 16,313 || 13–6 || L1 |-style="background:#cfc;" | 20 || April 30 || 6:35p.m. CDT || @ Phillies || W 1–0 || Scott (3–2) || Gross (1–3) || Smith (7) || 2:38 || 17,134 || 14–6 || W1 |- |-style="background:#cfc;" | 21 || May 2 || 2:35p.m. CDT || @ Expos || W 6–3 || Knepper (5–0) || Youmans (0–3) || Smith (8) || 2:38 || 6,781 || 15–6 || W2 |-style="background:#fcc;" | 22 || May 3 || 12:35p.m. CDT || @ Expos || L 6–7 || Reardon (3–2) || DiPino (0–1) || — || 3:45 || 11,769 || 15–7 || L1 |-style="background:#fcc;" | 23 || May 4 || 2:05p.m. CDT || @ Expos || L 6–7 || Reardon (4–2) || Smith (0–1) || — || 3:01 || 13,810 || 15–8 || L2 |-style="background:#fcc;" | 24 || May 6 || 6:35p.m. CDT || @ Mets || L 0–4 || Gooden (5–0) || Knepper (5–1) || — || 2:36 || 41,722 || 15–9 || L3 |-style="background:#fcc;" | 25 || May 7 || 6:35p.m. CDT || @ Mets || L 2–3 || Fernandez (4–0) || Ryan (3–4) || Orosco (6) || 2:42 || 26,956 || 15–10 || L4 |-style="background:#cfc;" | 26 || May 9 || 6:35p.m. CDT || @ Pirates || W 3–2 || Kerfeld (3–0) || Winn (1–1) || Smith (9) || 2:27 || 17,296 ||