In areas of intensive game management that included big game fencing, supplementary feeding locations, and grazing livestock, cases of tuberculosis lesions in wild red deer and wild boars appeared. Some boars and deer shared the same strains of tuberculosis which were similar to those found in livestock and humans suggesting a possible sapronotic or sapro-zoonotic contamination of shared water sources, supplemental feed, direct contact with humans or livestock, or their excretions. Domesticated companionship animals E. coli Dogs, horses: Evidence of infection by human E. coli strains in several dogs and horses across Europe was found, thus implicating the possibility of zoonotic inter-special transmission of multiresistant strains from humans to companion animals and vice versa. Tuberculosis Dog: A Yorkshire terrier was admitted into a veterinary clinic with a chronic cough, poor weight retention, and vomiting being reported for months where it was revealed that the owner had recovered from tuberculosis, however the dog initially tested negative for tuberculosis in 2 different molecular assays and was discharged. 8 days later the dog was euthanized because of a urethral obstruction. A necroscopy was performed where liver and tracheobronchial lymph node samples in fact tested positive for the exact same strain of tuberculosis the owner had previously. This is a very clear case of reverse zoonosis. Influenza A virus subtype H1N1 Ferrets: Ferrets are often used in human clinical studies thus the potential for human influenza to infect them was previously confirmed. However confirmation of natural transference of a human H1N1 strain from the 2009 outbreak in household pet ferrets further implicates human to animal transference. COVID-19 Amidst the 2020 global pandemic of COVID-19, susceptibility of cats, ferrets, dogs, chickens, pigs, and ducks to the SARS-CoV-2 coronavirus was examined and it was found that it can be replicated in cats and ferrets with lethal results. Cats: The virus can be transmitted in the air between cats. Viral RNA was detected in feces within 3–5 days of infection and pathological studies detected viral RNA in the soft palate, tonsils, and trachea. Kittens acquired massive lesions in the lungs, nasal and tracheal mucosa epitheliums. Surveillance for SARS-CoV-2 in cats should be considered as an adjunct to elimination of COVID-19 in humans. Ferrets: Ferrets were inoculated with viral strains from the environment of the Huanan Seafood Market in Wuhan, China as well as human isolates from Wuhan. It was found that with both isolates, that the virus