arthritis patients in the towns of Lyme and Old Lyme, CT, and scientists at the Station were among the first to determine that this disease was carried by ticks. After this discovery, scientists at the Station, including Dr. John F. Anderson and Dr. Louis A. Magnarelli (former Station Directors) along with collaborators from other institutions were able to isolate and identify the spirochete that causes Lyme disease in humans. Scientists at the Station were also instrumental in developing antibody tests to identify patients infected with Lyme disease agent as well as other tick-borne illnesses such as human granulocytic erlichiosis and babesiosis. Timeline of significant events 1875: The Connecticut Agricultural Experiment Station is established; the first in the United States, and precursor for the nation's industrial research laboratories; founded twenty-five years prior to the General Electric laboratories, which was the first of its kind. 1882: The Station moves to its current location on Huntington Street in New Haven, land purchased from the Eli Whitney, Jr. family 1890: Dr. Roland Thaxter, botanist at the Station, determines the cause of potato scab (an actinomycete that infects tubers). 1900: Sumatran tobacco was planted under cloth canopies in Connecticut in an effort to simulate Sumatra's tropical climate. The resulting shade grown tobacco was considered second to none for making cigar wrappers and consequently revolutionized the industry in the Connecticut Valley. 1903: State entomologist William E. Britton and G. P. Clinton issue the first pesticide “spray calendar” to be used by Connecticut farmers. 1905: The first gypsy moth discovered in Connecticut was found in Stonington, CT by E. Frensch of Mystic, CT. A female specimen, collected on July 25, was given to W. E. Britton and is still present in the Station's insect collection. 1907: Chestnut blight first seen in Connecticut. 1913: Thomas B. Osborne, chemist at the Station, and Lafayette B. Mendel of Yale University demonstrate with rat feeding studies that animals require twenty essential amino acids in their diet, and identify a “yellow substance” in butterfat vital for animal growth, which turned out to be Vitamin A 1917: The first hybrid corn using a four-way cross made by geneticist Donald F. Jones. He also publishes the theory of “heterosis” to explain hybrid vigor in corn. 1919: Jones invents a double cross pollination method, which allows for commercial production of hybrid corn. 1921: The Valley Laboratory established in Windsor, CT (called Tobacco Substation at the