(1–3) || || 34,669 || 23–21 |- align="center" bgcolor="#bbffbb" | 45 || May 20 || Reds || 4–1 || Billingsley (4–5) || Belisle (1–4) || Saito (7) || 34,306 || 24–21 |- align="center" bgcolor="#bbffbb" | 46 || May 21 || Reds || 5–2 || Kuroda (2–3) || Cueto (2–5) || Saito (8) || 33,224 || 25–21 |- align="center" bgcolor="#ffbbbb" | 47 || May 23 || Cardinals || 2–1 || Wainwright (4–2) || Lowe (2–5) || Franklin (3) || 52,281 || 25–22 |- align="center" bgcolor="#ffbbbb" | 48 || May 24 || Cardinals ||4–0 || Lohse (4–2)|| Penny (5–5)|| ||44,785 ||25–23 |- align="center" bgcolor="#bbffbb" | 49 || May 25 || Cardinals || 4–3 (10) || Saito (3–1) || Parisi (0–1) || || 46,566 || 26–23 |- align="center" bgcolor="#ffbbbb" | 50 || May 26 || @ Cubs || 3–1|| Dempster (6–2) ||Billingsley (4–6) || Wood (11)||41,583 ||26–24 |- align="center" bgcolor="#ffbbbb" | 51 || May 27 || @ Cubs || 3–1 || Gallagher (2–1)|| Kuroda (2–4) || Wood (12) || 39,894 || 26–25 |- align="center" bgcolor="#ffbbbb" | 52 || May 28 || @ Cubs || 2–1 (10) || Howry (1–2) || Park (1–1)|| || 39,945 || 26–26 |- align="center" bgcolor="#ffbbbb" | 53 || May 29 || @ Mets || 8–4 || Vargas (2–2) || Penny (5–6) || || 52,886 || 26–27 |- align="center" bgcolor="#bbffbb" | 54 || May 30 || @ Mets || 9–5 || Park (2–1) || Heilman (0–2) || || 52,176 || 27–27 |- align="center" bgcolor="#ffbbbb" | 55 || May 31 || @ Mets || 3–2 || Sánchez (2–0) || Broxton (2–2)|| Wagner (11) || 53,528 || 27–28 |- |- align="center" bgcolor="#ffbbbb" | 56 || June 1 || @ Mets || 6–1 || Santana (7–3) || Kuroda (2–5) || ||50,263 ||27–29 |- align="center" bgcolor="#bbffbb" | 57 || June 2 || Rockies || 8–2 ||Lowe (3–5) || Reynolds (0–3) || ||39,098 ||28–29 |- align="center" bgcolor="#ffbbbb" | 58 || June 3 || Rockies || 3–0 || Francis (2–5) ||Penny (5–7) ||Fuentes (7) || 38,548||28–30 |- align="center" bgcolor="#ffbbbb" | 59 || June 4 || Rockies || 2–1|| Cook (8–3)||Kershaw (0–1) || Fuentes (8)|| 36,393||28–31 |- align="center" bgcolor="#ffbbbb" | 60 || June 5 || Cubs ||5–4 ||Howry (2-2) ||Saito (3–2) || Wood (17) ||44,988 ||28–32 |- align="center" bgcolor="#bbffbb" | 61 || June 6 || Cubs ||3–0 ||Kuroda (3–5) || Gallagher (3–2) || ||52,484 ||29–32 |- align="center" bgcolor="#bbffbb" | 62 || June 7 || Cubs || 7–3