|| Eckersley (5) || 33,172 || 12–6 |- style="text-align:center;background-color:#bbffbb" | 19 || April 23 || Angels || 2–0 || Moore (2–1) || McCaskill (3–1) || Eckersley (6) || 25,681 || 13–6 |- style="text-align:center;background-color:#bbffbb" | 20 || April 24 || Blue Jays || 5–4 || Nelson (1–0) || Henke (1–2) || || 25,099 || 14–6 |- style="text-align:center;background-color:#bbffbb" | 21 || April 25 || Blue Jays || 3–1 || Davis (2–1) || Cerutti (0–1) || Eckersley (7) || 12,437 || 15–6 |- style="text-align:center;background-color:#ffbbbb" | 22 || April 26 || Orioles || 2–1 || Bautista (2–2) || Welch (3–2) || Olson (2) || 17,060 || 15–7 |- style="text-align:center;background-color:#bbffbb" | 23 || April 27 || Orioles || 9–4 || Burns (1–0) || Thurmond (0–1) || || 21,423 || 16–7 |- style="text-align:center;background-color:#bbffbb" | 24 || April 28 || Tigers || 2–1 || Moore (3–1) || Gibson (1–1) || Eckersley (8) || 26,594 || 17–7 |- style="text-align:center;background-color:#bbffbb" | 25 || April 29 || Tigers || 3–2 || Stewart (5–0) || Alexander (3–1) || || 36,313 || 18–7 |- style="text-align:center;background-color:#ffbbbb" | 26 || April 30 || Tigers || 7–2 || Tanana (2–3) || Davis (2–2) || Hernández (5) || 36,009 || 18–8 |- style="text-align:center;background-color:#bbffbb" | 27 || May 2 || @ Blue Jays || 8–5 || Honeycutt (1–0) || Ward (1–4) || Plunk (1) || 23,439 || 19–8 |- style="text-align:center;background-color:#ffbbbb" | 28 || May 3 || @ Blue Jays || 2–0 || Flanagan (2–1) || Moore (3–2) || || 22,370 || 19–9 |- style="text-align:center;background-color:#bbffbb" | 29 || May 5 || @ Tigers || 5–3 || Stewart (6–0) || Tanana (2–4) || Eckersley (9) || 18,482 || 20–9 |- style="text-align:center;background-color:#ffbbbb" | 30 || May 6 || @ Tigers || 6–3 || Morris (1–6) || Davis (2–3) || Hernández (6) || 32,404 || 20–10 |- style="text-align:center;background-color:#bbffbb" | 31 || May 7 || @ Tigers || 5–4 || Welch (4–2) || Hudson (0–3) || Eckersley (10) || 20,391 || 21–10 |- style="text-align:center;background-color:#bbffbb" | 32 || May 8 || @ Orioles || 6–1 || Moore (4–2) || Milacki (1–3) || || 19,159 || 22–10 |- style="text-align:center;background-color:#ffbbbb" | 33 || May 11 || @ Orioles || 6–2 || Ballard (6–1) || Stewart (6–1) || || 1,201 || 22–11 |- style="text-align:center;background-color:#bbffbb" | 34 || May 12 || Brewers || 5–4 || Burns (2–0) || Plesac (1–2) || || 30,743 || 23–11 |- style="text-align:center;background-color:#bbffbb" | 35 || May 13 || Brewers || 4–3 ||