Isthmura gigantea, commonly known as the giant false brook salamander, is a species of salamander in the family Plethodontidae. It is endemic to Mexico and known from the eastern margins Sierra Madre Oriental between north-eastern Hidalgo and northern Puebla and central Veracruz near Xalapa. The natural habitat of this terrestrial species is the pine-oak/cloud forest interface at elevations of above sea level. It tolerates some habitat disturbance but is threatened from severe habitat loss from logging, mining, agriculture, and human settlement that is occurring within its range. References gigantea Amphibians described in 1939 Endemic amphibians of Mexico Fauna of the Sierra Madre Oriental Taxonomy articles created by Polbot