April 5 || Mariners || 11–1 || Welch (1–0) || Bankhead (0–1) || || 16,045 || 2–0 |- style="text-align:center;background-color:#bbffbb" | 3 || April 6 || Mariners || 11–3 || Davis (1–0) || Campbell (0–1) || Burns (1) || 19,087 || 3–0 |- style="text-align:center;background-color:#ffbbbb" | 4 || April 7 || White Sox || 7–1 || Long (1–0) || C. Young (0–1) || Jones (1) || 20,585 || 3–1 |- style="text-align:center;background-color:#ffbbbb" | 5 || April 8 || White Sox || 7–4 || Pérez (1–0) || Moore (0–1) || Thigpen (1) || 32,881 || 3–2 |- style="text-align:center;background-color:#bbffbb" | 6 || April 9 || White Sox || 4–2 || Stewart (2–0) || Reuss (1–1) || Eckersley (2) || 45,110 || 4–2 |- style="text-align:center;background-color:#bbffbb" | 7 || April 10 || @ Angels || 4–0 || Welch (2–0) || Finley (1–1) || || 23,820 || 5–2 |- style="text-align:center;background-color:#ffbbbb" | 8 || April 11 || @ Angels || 7–1 || Blyleven (1–0) || Davis (1–1) || || 23,322 || 5–3 |- style="text-align:center;background-color:#ffbbbb" | 9 || April 12 || @ Angels || 5–0 || McCaskill (2–0) || C. Young (0–2) || || 24,650 || 5–4 |- style="text-align:center;background-color:#bbffbb" | 10 || April 13 || @ Angels || 5–0 || Moore (1–1) || Abbott (0–2) || || 24,137 || 6–4 |- style="text-align:center;background-color:#bbffbb" | 11 || April 14 || @ White Sox || 7–4 || Stewart (3–0) || Pérez (1–1) || || 37,950 || 7–4 |- style="text-align:center;background-color:#ffbbbb" | 12 || April 15 || @ White Sox || 7–4 || Reuss (2–1) || Welch (2–1) || Thigpen (3) || 15,748 || 7–5 |- style="text-align:center;background-color:#bbffbb" | 13 || April 16 || @ White Sox || 3–2 || Eckersley (1–0) || King (0–3) || || 20,969 || 8–5 |- style="text-align:center;background-color:#ffbbbb" | 14 || April 17 || @ Mariners || 7–2 || Hanson (2–1) || C. Young (0–3) || || 14,827 || 8–6 |- style="text-align:center;background-color:#bbffbb" | 15 || April 18 || @ Mariners || 5–3 || Plunk (1–0) || Reed (1–2) || Eckersley (3) || 9,670 || 9–6 |- style="text-align:center;background-color:#bbffbb" | 16 || April 19 || @ Mariners || 7–5 || Stewart (4–0) || Langston (2–2) || Eckersley (4) || 11,328 || 10–6 |- style="text-align:center;background-color:#bbffbb" | 17 || April 21 || Angels || 10–6 || Welch (3–1) || Finley (2–2) || Honeycutt (1) || 26,903 || 11–6 |- style="text-align:center;background-color:#bbffbb" | 18 || April 22 || Angels || 4–3 || C. Young (1–3) || Blyleven (2–1)