|| — || 17,182 || 65–72 |- bgcolor="ccffcc" | 138 || August 31 || Red Sox || 8–0 || Adams (2–2) || Wakefield || — || 32,116 || 66–72 |- |- bgcolor="ffbbbb" | 139 || September 1 || Red Sox || 3–8 || Sele || Wasdin (7–7) || — || 15,021 || 66–73 |- bgcolor="ffbbbb" | 140 || September 2 || Yankees || 0–5 || Cone || Prieto (4–7) || — || 20,159 || 66–74 |- bgcolor="ccffcc" | 141 || September 3 || Yankees || 10–9 || Acre (1–2) || Boehringer || Johns (1) || 11,621 || 67–74 |- bgcolor="ffbbbb" | 142 || September 4 || Yankees || 3–10 || Pettitte || Telgheder (2–6) || — || 9,892 || 67–75 |- bgcolor="ccffcc" | 143 || September 6 || Royals || 7–1 || Adams (3–2) || Haney || — || 14,404 || 68–75 |- bgcolor="ccffcc" | 144 || September 7 || Royals || 13–6 || Prieto (5–7) || Belcher || — || 13,175 || 69–75 |- bgcolor="ccffcc" | 145 || September 8 || Royals || 8–7 (10) || Corsi (6–0) || Pichardo || — || 17,208 || 70–75 |- bgcolor="ccffcc" | 146 || September 10 || @ Twins || 7–0 || Telgheder (3–6) || Robertson || — || 9,676 || 71–75 |- bgcolor="ffbbbb" | 147 || September 11 || @ Twins || 2–7 || Radke || Adams (3–3) || — || 9,493 || 71–76 |- bgcolor="ffbbbb" | 148 || September 12 || @ Twins || 3–4 (12) || Stevens || Mohler (5–3) || — || 9,712 || 71–77 |- bgcolor="ffbbbb" | 149 || September 14 || @ Indians || 2–9 || Nagy || Wengert (7–10) || — || — || 71–78 |- bgcolor="ffbbbb" | 150 || September 14 || @ Indians || 8–9 || Plunk || Small (0–2) || Mesa || 42,233 || 71–79 |- bgcolor="ccffcc" | 151 || September 15 || @ Indians || 10–9 (10) || Reyes (7–10) || Mesa || — || 42,226 || 72–79 |- bgcolor="ccffcc" | 152 || September 17 || @ Angels || 5–1 || Prieto (6–7) || Springer || — || 17,827 || 73–79 |- bgcolor="ffbbbb" | 153 || September 18 || @ Angels || 1–3 || Finley || Adams (3–4) || Percival || 18,213 || 73–80 |- bgcolor="ffbbbb" | 154 || September 20 || @ Mariners || 2–12 || Carmona || Wengert (7–11) || Meacham || 56,535 || 73–81 |- bgcolor="ffbbbb" | 155